DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and Ugt37A2

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_650228.1	Gene:	Ugt37A2 / 41573	FlyBaseID:	FBgn0038082	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	550	Identity:	135/550 - (24%)
Similarity:	232/550 - (42%)	Gaps:	76/550 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYT------GHGLGE 66
            ::|||.....||. ...|.||.:|..::..|..:..:....||.|.|.:.|.|      .|
  Fly     8 YLLLATAICVLGG-CHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNH---- 67

  Fly    67 SLDNVTETVTAEFPFWSELQKQ------AAPKGNLADLGLLPIEKLRQ------SLASVGARALD 119
              .|:|..:.   |...|..:|      |..|.:.:::.|..:..:.|      .:|  ||
  Fly    68 --KNITVIMV---PLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMA--GA---- 121

  Fly   120 HFLAQEPIQKLLKMSYLEFD--FDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYM------ 176
              |..:.::.|    ||..|  ||::|..||.....|......:.||: :::|...|.:
  Fly   122 --LKDDRVRDL----YLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVI-VVATMPPNQLLNPLIG 179

  Fly   177 DAVQEALVPAACSPIDFERDQPEMSFSVRLGNIRTCI----------ARRKQFIKDHYGGQEQLV 231
            :.::.|.||:....::..:.   |||..||....:..          .|.|:..|:.:|....:
  Fly   180 NPLEIAYVPSISDSVEKGKG---MSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNM- 240

  Fly   232 TKYFQLQSSIPELQASQLSVLLLNSHVPLITP-KVSIQQIIPAGGLHIRG-PKELPWNVKRFLEE 294
            .:|.:|        ....|::...||.|...| :.::...|..||:.::. |..||.|:..||..
  Fly   241 PEYSEL--------VKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGN 297

  Fly   295 ARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQID 359
            |..|||.:.||:......:..:.:..:|...|..||.:||...|::...|...|:.....:||.|
  Fly   298 ATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDD 362

  Fly   360 ILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLN 424
            |||||.:|.|:.:.....:.|......|:|.||:|..:..|.::.|:.|.||.....::..:...
  Fly   363 ILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFK 427

  Fly   425 WAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLF 489
            .|:..:|....:...:...|..:||||:.|..|.::|..||.||.|.:.|::..:.:|....:..
  Fly   428 EAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAANNI 492

  Fly   490 DLFVFYAGIATLVVSLLVALSFGGFYIWNK 519
            |:   ||.||.::|.|::.|.....:|:.|
  Fly   493 DI---YALIAVVLVILVLLLKLLLQFIYRK 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	119/492 (24%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	128/526 (24%)
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	125/516 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020