DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and Ugt316A1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001287111.1	Gene:	Ugt316A1 / 40079	FlyBaseID:	FBgn0036842	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	143/555 - (25%)
Similarity:	245/555 - (44%)	Gaps:	67/555 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTEL--ANREHTIEVYTGHGLGESLDNV 71
            ||...||..|..|...|.:|.:||.|.:.|:...|.|:.||  ::..|::.:.:.|...|.:|
  Fly     3 ILQVFLGTLLCGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVD-- 65

  Fly    72 TETVTAEFPFWSELQKQAAPKGNLADLGL-LPIEKLR-QS-------LASVGARALDHFLAQEPI 127
                 ||.|...||:.:.. :.|..|:|: ...|::| ||       |...|...:|..|:...:
  Fly    66 -----AEIPKIRELRIEGL-RENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQV 124

  Fly   128 QKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPAACSPID 192
            :|||....   .||:::||.|.::|||.|...:..|.|.:..|...::::.:......::..|.:
  Fly   125 RKLLTSGE---KFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSN 186

  Fly   193 FERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPELQ-----ASQLSVL 252
            |......|:...|:.|.......|..:...|...|:.:.|.:|:|  .:.||.     ...||:.
  Fly   187 FLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFEL--LVKELPLYRDLTKNLSLA 249

  Fly   253 LLNSHVPLITPKVSIQQIIPAGGLHIR--GPKELPWNVKRFLEEARPGAIYVQLGNEQACGQLPK 315
            |:|||..|..|:..:..::..||||:.  ....||.::..|:|.|..|.||..||.:....|||:
  Fly   250 LINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQ 314

  Fly   316 EKLDTLFAFFSARKQ---SIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLN 377
            |||..:...|...|:   .:.|...:....:.||:||||....||..||.||:||.|:::...|:
  Fly   315 EKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLS 379

  Fly   378 LQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHF-----Q 437
            :.|.|....|:|.:|:...:....:...|.||.:.:...::..:||...:.:|.|.:.:     |
  Fly   380 VWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQ 444

  Fly   438 LTIRDVSLEFRD-RPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATL 501
            |..|.:|   || .|:|   .|:..:..:....|...|::....::..:....|
  Fly   445 LKERLIS---RDSTPVG---KAVRKIQLILESGGADFLKSHANTLNFWRAEGVD----------- 492

  Fly   502 VVSLLVALSFGGF---------YIWNKKNNSKSTK 527
             |.|::|:.|.|.         :|..|..:|::.:
  Fly   493 -VLLIIAVGFFGILTIPFLAICFILRKSYHSQAAQ 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	128/481 (27%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	133/515 (26%)
Ugt316A1	NP_001287111.1	egt	1..480	CDD:223071	134/495 (27%)
Ugt316A1	NP_001287111.1	MGT	39..448	CDD:273616	112/421 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.920