Protein Alignment Ugt317A1 and Ugt1a6b

DIOPT Version :9

• Sequence 1: NP_001286734.1
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 566
• Identity: 136/566 - (24%)
• Similarity: 231/566 - (40%)
• Gaps: 98/566 - (17%)

  Fly     8 WILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHG---LGESLD 69
            ::.|.:....||.     |:||: |. :..|:..|:.:|..|:.|.|.|.|.....   ||||..
Mouse    15 FLFLVLWASVLGD-----KLLVV-PQ-DGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKY 72

  Fly    70 NVTETVTAEFPFWSELQ--------KQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEP 126
            ...:..:..:.. .|||        .|..|...|  :|  |:.:.|.|:.:     |:.|.:.
Mouse    73 YRRKIFSVPYSL-EELQTRFRTFGRNQFVPGAPL--MG--PLREYRNSMLT-----LEMFFSN-- 125

  Fly   127 IQKLLK----MSYL-EFDFDVILVDYFYTEALLALGALHQRPVV--GIISTDFGN----YM---- 176
            .|.|||    :|:| |..||.:..|                |.:  |:|..::.|    |:
Mouse   126 CQSLLKDSATLSFLRENKFDALFTD----------------PAMPCGVILAEYLNLPSVYLFRGF 174

  Fly   177 DAVQEALVPAACSPID-----FERDQPEMSFSVRLGN---------IRTCIARRKQFIKDHYGGQ 227
            ....|.::..:.||:.     :.:....|:|..||.|         :..|:          |...
Mouse   175 PCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCL----------YSKY 229

  Fly   228 EQLVTKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFL 292
            |.:||...:...|:|.|.  |.|:.||........|:..:..:|..||::.:...:|....:.::
Mouse   230 EIIVTDLLKRDVSLPSLH--QNSLWLLRYDFVFEYPRPIMPNMIFIGGINCKKKGKLTQEFEAYV 292

  Fly   293 E-EARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVP 356
            . ....|.:...||:  ...::|::|...:........|:::|.....:. ..|.||.::...:|
Mouse   293 NASGEHGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRP-SNLAKNTILVKWLP 354

  Fly   357 QIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTE 421
            |.|:|.||:.:||:|:.....:.|||...||::.:|||..:..|.:.....|.|:.|....:|.:
Mouse   355 QNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTAD 419

  Fly   422 SLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQL 486
            .|..|:..::....::..|..:|...:|||:..|..|:|||.||.||||...||.....::..|.
Mouse   420 DLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQY 484

  Fly   487 HLFDLFVFYAGIATLVVSLLVAL-------SFGGFYIWNKKNNSKS 525
            |..|:..|...|...||.::...       .|||.....|.:.||:
Mouse   485 HSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKT 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	120/495 (24%)
		UDPGT	25..514	CDD:278624	129/536 (24%)
Ugt1a6b	NP_958812.3	egt	15..503	CDD:223071	130/537 (24%)
		UDPGT	27..522	CDD:278624	130/544 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810