Protein Alignment Ugt317A1 and Ugt1a7c

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_964004.1
• Gene: Ugt1a7c / 394432
• MGIID: 3032636
• Length: 531
• Species: Mus musculus
• Alignment Length: 547
• Identity: 131/547 - (23%)
• Similarity: 231/547 - (42%)
• Gaps: 59/547 - (10%)

  Fly    10 LLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVY---TGHGLGESLDNV 71
            |...|.||.| ::||.::||:  .::..|:..|:|:|.:|.::.|.:.|.   ....|.:.|:.|
Mouse    12 LCVCLLLASG-LAQAGRLLVV--PMDGSHWFTMQTVVEKLLHKGHEVVVVVPEVSWQLTKPLNFV 73

  Fly    72 TET---------VTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEPI 127
            .:|         :..||..:.:.|.::..:|     |:||:  |.............|..:....
Mouse    74 VKTYAVSHTQEDLNREFKIFIDAQWKSQQEG-----GILPL--LDSPAKGFFELLFSHCRSLFND 131

  Fly   128 QKLLKMSYL-EFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPAACSPI 191
            :||::  || :..||.:.:|.| ....|.:......|.|......|.:|::...:...|.:..|.
Mouse   132 KKLVE--YLKQTSFDAVFLDPF-DVCGLTVAKYFSLPSVVFSRGIFCHYLEDAAQCPSPPSYIPR 193

  Fly   192 DFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPE--LQA-------- 246
            ...:....|:|..|..|:..            |.|:.....|:|:..:.|..  ||.
Mouse   194 MLLKFTDTMTFKERTRNLLA------------YMGERAFCHKFFKSAADIASEVLQTPVTMTDLF 246

  Fly   247 SQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLE-EARPGAIYVQLGNEQAC 310
            |.:|:.||.:...|..|:..:..:|..||::....|.|....:.::. ....|.:...||:  ..
Mouse   247 SPVSIWLLRTDFVLEFPRPVMPNVIYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGS--MV 309

  Fly   311 GQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDL 375
            .::|::|...:........|:::|.....:. ..|.||.::...:||.|:|.||:.:||:|:...
Mouse   310 SEIPEKKAMEIAEALGRIPQTVLWRYTGTRP-SNLAKNTILVKWLPQNDLLGHPKTRAFITHSGS 373

  Fly   376 LNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTI 440
            ..:.|||...||::.:|||..:..|.:.....|.|:.|....:|.:.|..|:..::....::..|
Mouse   374 HGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENI 438

  Fly   441 RDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSL 505
            ..:|...:|||:..|..|:|||.||.||||...||.....::..|.|..|:..|...|...||.:
Mouse   439 MRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFI 503

  Fly   506 LVAL-------SFGGFYIWNKKNNSKS 525
            :...       .|||.....|.:.||:
Mouse   504 VFKCCAYGCRKCFGGKGRVKKSHKSKT 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	93/429 (22%)
Ugt1a7c	NP_964004.1	UDPGT	26..522	CDD:278624	121/522 (23%)