Protein Alignment Ugt317A1 and Ugt1a10

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_964003.2
• Gene: Ugt1a10 / 394430
• MGIID: 3580642
• Length: 530
• Species: Mus musculus
• Alignment Length: 550
• Identity: 132/550 - (24%)
• Similarity: 235/550 - (42%)
• Gaps: 66/550 - (12%)

  Fly    10 LLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVY---TGHGLGESLD-- 69
            |...|.||.|.: ||.::||:  .::..|:..|:.:|.:|..|.|.:.|.   ....||:||:
Mouse    12 LCVCLLLASGLV-QAGRLLVV--PMDGSHWFDMQMVVEKLIQRGHEVVVVIPEVSWRLGKSLNCT 73

  Fly    70 -------NVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARA-----LDHFL 122
                   :..|.:..||.:::..|.:.            |.:.:| |..:..||.     ..|..
Mouse    74 VKTYSVSHTLEDLDREFKYFTYTQWKT------------PEQSIR-SFMTGSARGFFELMFSHSR 125

  Fly   123 AQEPIQKLLKMSYL-EFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPA 186
            .....:||::  || :..||.:.:|.|....|:....| ..|.|......|..|::  :.|..|:
Mouse   126 GLFNDKKLVE--YLKQRSFDAVFLDPFDVCGLIVAKYL-SLPSVIFARLSFCYYLE--EGAQCPS 185

  Fly   187 ACS--PIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDH------YGGQEQLVTKYFQLQSSIPE 243
            ..|  |..|.:....|:|..|:.|       ...:|:|:      :....::.::..|...::.:
Mouse   186 LLSYVPRLFSKYTDTMTFKERVWN-------HYMYIEDYVFCPYFFKTAVEIASEVLQTPVTMTD 243

  Fly   244 LQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLE-EARPGAIYVQLGNE 307
            | .|.:|:.||.:...|..|:..:..::..||::....|.|....:.::. ....|.:...||:
Mouse   244 L-FSPVSIWLLRTDFVLEFPRPVMPNMVFVGGMNCLQGKPLSKEFEAYVNASGEHGIVVFSLGS- 306

  Fly   308 QACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTN 372
             ...::|::|...:........|:::|.....:. ..|.||.::...:||.|:|.||:.:||:|:
Mouse   307 -MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRP-SNLAKNTILVKWLPQNDLLGHPKTRAFITH 369

  Fly   373 GDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQ 437
            .....:.|||...||::.:|||..:..|.:.....|.|:.|....:|.:.|..|:..::....::
Mouse   370 SGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYK 434

  Fly   438 LTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLV 502
            ..|..:|...:|||:..|..|:|||.||.||||...||.....::..|.|..|:..|...|...|
Mouse   435 ENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTV 499

  Fly   503 VSLLVAL-------SFGGFYIWNKKNNSKS 525
            |.::...       .|||.....|.:.||:
Mouse   500 VFIVFKCCAYGCRKCFGGKGRVKKSHKSKT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	94/432 (22%)
Ugt1a10	NP_964003.2	UDPGT	26..521	CDD:278624	122/525 (23%)