DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and Ugt36E1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	545	Identity:	148/545 - (27%)
Similarity:	246/545 - (45%)	Gaps:	100/545 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WNRWILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEV----------- 58
            |..:.|||:|.|.  ..|.:.:||.||||....||.....::..||...|:::|
  Fly     5 WKVFCLLALLSLV--AFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPN 67

  Fly    59 -YTGHGLGESLDNVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFL 122
             |..|.|..|  .:|:|::.|     :.::..:...:..:..:|..........::.:|||...|
  Fly    68 GYKDHLLPPS--TLTDTISLE-----DFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALTEIL 125

  Fly   123 AQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIIS--------TDFGNYMDAV 179
            ...|       .|    :||||::.|.|:..:::..:.|.||:|:.|        ..||
  Fly   126 KNPP-------GY----YDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERFG------ 173

  Fly   180 QEALVPAACSPIDFERDQPEMSFSVRLGN---IRTCIARRKQF--------IKDHYG----GQEQ 229
             ..|:|:..|.: |:....||||:.||||   :.:.....|.|        |:..:|    ..|.
  Fly   174 -APLIPSYISAL-FQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTED 236

  Fly   230 LVTKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEE 294
            ||               ...|::|:|.|..|..||.....:|..||:||..||.||.::::.|:.
  Fly   237 LV---------------RNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDN 286

  Fly   295 ARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQID 359
            |..|.|.:..|::.....|...:.|.:.......:|.:||. ::..||...|.|:.|:..:||.|
  Fly   287 APKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWK-YENDTLPNKPPNLHIRKWLPQRD 350

  Fly   360 ILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLE----EGNVTT 420
            |||||.:|.|:::|.|:...|.:...|||:|:|::..::.|:...|:.|:.||||    :.|...
  Fly   351 ILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVY 415

  Fly   421 ESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQ 485
            |:|..|:|     ..|:...::|:..:.:|..|.|.:|::||.:||..||....:...:.:|.
  Fly   416 EALTKALD-----PSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSR-- 473

  Fly   486 LHLFDLFVFYAGIATLVVSLLVALS 510
                  ||:|    :|.|..:||||
  Fly   474 ------FVYY----SLDVYSVVALS 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	132/493 (27%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	141/525 (27%)
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	136/503 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060