DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and Ugt36D1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	144/548 - (26%)
Similarity:	231/548 - (42%)	Gaps:	82/548 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WNRWILLAILGLALGQ---ISQAA---KILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHG 63
            |:..:.|..|.|||.|   :.:||   |:|.||||....||.....::..||...|.:
  Fly     2 WSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDV------- 59

  Fly    64 LGESLDNVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQS------------------- 109
                      :|.:.||       ...|..:..|..|..::||..|
  Fly    60 ----------SVVSHFP-------DKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFF 107

  Fly   110 -LASVGARALDHFLAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIIS-TDF 172
             |...|.:..:..|..|.:|::|:.   ...||||:::.|.|:.::.:....|.||:.:.| ...
  Fly   108 LLYDWGKQTCNLTLRSEALQQILRR---PGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMM 169

  Fly   173 GNYMDAVQEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVT-KYFQ 236
            ..:.:.:...|:|:.. |..|......|:|..||.|..:..|....:........:.:|. |:..
  Fly   170 PWHYERMGAPLIPSHI-PALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGH 233

  Fly   237 LQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEARPGAIY 301
            ...|:.|| ....|:..:|.|..|..|||:...:|..||:||:..|.||.:::|.|:.|..|.|.
  Fly   234 DVPSVGEL-VKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDNAEEGVIL 297

  Fly   302 VQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRV 366
            :..|:......|...|.|.:....:..||.:||...: :||...|.|:.|...:||.|||.||.|
  Fly   298 ISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWEN-ETLPNQPPNMHIMKWLPQRDILCHPNV 361

  Fly   367 KAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVG--LQLEE--GNVTTESLNWAV 427
            |.|:::|.|:...|.....||::..|::..:..|....|..|:|  |..|:  .|....:|..|:
  Fly   362 KVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKAL 426

  Fly   428 DRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLF 492
            |:     .|....:.||..|..||..||.:|::||.:||...|...|:...:.:|.        |
  Fly   427 DK-----KFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSR--------F 478

  Fly   493 VFYAGIATLVVSLLVALSFGGF---YIW 517
            |:|    :|.|..::||..|..   ::|
  Fly   479 VYY----SLDVYAVLALVLGSIIASWVW 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	127/483 (26%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	135/517 (26%)
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	131/507 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060