Protein Alignment Ugt317A1 and Ugt2b10

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001178605.1
• Gene: Ugt2b10 / 305264
• RGDID: 1309989
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 124/517 - (23%)
• Similarity: 217/517 - (41%)
• Gaps: 34/517 - (6%)

  Fly    12 AILGLALGQISQ------AAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVY-TGHGLGESLD 69
            |.|.|.|.|:|.      ..|:|| :| :...|:..:|.::.||..:.|.:.|. ....|...:|
  Rat     7 ASLLLLLLQLSDFFGSGTGGKVLV-WP-MEFSHWLNLRVILDELLKKGHEVTVLRPSASLSYEVD 69

  Fly    70 NVTETVTAEFP-----------FWSELQK--QAAPKGNLADLGLLPIEKLRQSLASVGARALDHF 121
            |.:......:|           ||..|:|  ...||.:.....|     :.|.|..|.:...:..
  Rat    70 NTSAIEFETYPTSYSLTEVDEFFWESLRKYIYELPKQSFWGYFL-----MFQELVWVDSDYFESL 129

  Fly   122 LAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEAL-VP 185
            .......|.|........|||||.|.|.....| |..:.:.|:|..:....|:..:.....| :|
  Rat   130 CKDVVFNKELMTKLQNSGFDVILADPFIPCGDL-LAEILKIPLVYSLRFFPGSTYEKYSGGLPMP 193

  Fly   186 AACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPELQASQLS 250
            .:..||........|:|..|:.::...:.....|...:.....:|.|:.....:::.|..| :..
  Rat   194 PSYVPIAMSELSDRMTFVERMKHMIYVLCFDFWFQAFNEKKWNELYTEVLGRPTTLSETMA-KAD 257

  Fly   251 VLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEA-RPGAIYVQLGNEQACGQLP 314
            :.|:.::..|..|...:......||||.|..|.||..::.|::.: ..|.:...||:  ..|.|.
  Rat   258 IWLIRTYWDLEFPHPVLPNFDFVGGLHCRPAKPLPKEIEDFVQSSGEHGVVVFSLGS--MVGNLT 320

  Fly   315 KEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQ 379
            :|:.:.:.|..:...|.::|. .:.|..|.|..|..:...:||.|:|.||:.:||:|:|....:.
  Rat   321 EERANVIAAGLAQIPQKVLWR-FEGKKPETLGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIY 384

  Fly   380 EGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVS 444
            |.|...:|::|:|||..:..|:......|..::|:...:::..|..|:..:..:..::.....:|
  Rat   385 EAIYHGIPVVGIPLFGDQYDNIVHLKTKGAAVRLDFLTMSSTDLFTALKTITNDPSYKENAMRLS 449

  Fly   445 LEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSLL 506
            ....|:|:..|..|:||:.:|.||||...||.....:|..|.|..|:..|.......|:.:|
  Rat   450 RIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVIGFLLACVVTVMFIL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	97/421 (23%)
Ugt2b10	NP_001178605.1	UDPGT	26..529	CDD:278624	118/498 (24%)