Protein Alignment Ugt317A1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 131/551 - (23%)
• Similarity: 229/551 - (41%)
• Gaps: 67/551 - (12%)

  Fly     9 ILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEV--------------Y 59
            :||.:||   ...|.|.|:||:  .::..|:..|..::.:|..:.|.:.|              |
  Rat    17 LLLCVLG---PSASHAGKLLVI--PIDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFY 76

  Fly    60 TGHGLGESLDNVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSL---ASVGARALDHF 121
            |.........|  |.|||.|   .||.:....:    |..||.:.|....:   :|:......|.
  Rat    77 TMRKYPVPFQN--ENVTAAF---VELGRSVFDQ----DPFLLRVVKTYNKVKRDSSMLLSGCSHL 132

  Fly   122 LAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEAL--- 183
            |........|:.|:    ||.:|.|.|     |..|::    |...:|.....:::|:..:|
  Rat   133 LHNAEFMASLEQSH----FDALLTDPF-----LPCGSI----VAQYLSLPAVYFLNALPCSLDLE 184

  Fly   184 -----VPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFI-KDHYGGQEQLVTKYFQLQSSIP 242
                 .|.:..|.....:...|:|..|:.|:  .||..:.|: :..|.....|.|:..|.:.::.
  Rat   185 ATQCPAPLSYVPKSLSSNTDRMNFLQRVKNM--IIALTENFLCRVVYSPYGSLATEILQKEVTVK 247

  Fly   243 ELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLE-EARPGAIYVQLGN 306
            :| .|..|:.|:.:......|:..:..::..||::....|.|....:.::. ....|.:...||:
  Rat   248 DL-LSPASIWLMRNDFVKDYPRPIMPNMVFIGGINCLQKKALSQEFEAYVNASGEHGIVVFSLGS 311

  Fly   307 EQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLT 371
              ...::|::|...:........|:::|.....:. ..|.||.::...:||.|:|.||:.:||:|
  Rat   312 --MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRP-SNLAKNTILVKWLPQNDLLGHPKARAFIT 373

  Fly   372 NGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHF 436
            :.....:.|||...||::.:|||..:..|.:.....|.|:.|....:|.:.|..|:..::....:
  Rat   374 HSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSY 438

  Fly   437 QLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATL 501
            :..|..:|...:|||:..|..|:|||.||.||||...||.....::..|.|..|:..|...|...
  Rat   439 KENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLT 503

  Fly   502 VVSLL-------VALSFGGFYIWNKKNNSKS 525
            ||.::       ....|||.....|.:.||:
  Rat   504 VVFIVYKSCAYGCRKCFGGKGRVKKSHKSKT 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	94/432 (22%)
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	122/525 (23%)