DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and ugt-14

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_504316.1	Gene:	ugt-14 / 186767	WormBaseID:	WBGene00019233	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	561	Identity:	118/561 - (21%)
Similarity:	207/561 - (36%)	Gaps:	130/561 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ISQAAKILVLFPH---VNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVTETVTAEFPFW 82
            ::|.|.|:....|   :.:.:...|:.....:.||:..|..|..|........:.||.:.   .|
Worm    36 VTQMADIIADHGHNVTLFQPYHIAMKNTEGLVKNRKVNIINYYPHDFNTISGAMPETFSG---LW 97

  Fly    83 SELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEPIQKLLKMSYLEFDFDVILVDY 147
            .         ..|.:..:|....:.:::..|..:.....|..|.|.:.||..    .|:|::.:.
Worm    98 D---------SKLLNNAILSAYAMPKAIGRVFEKTATQLLQDESILEELKSR----KFEVVISEA 149

  Fly   148 F-YTEALLALGALHQRPVVGIIST----DFGNYMDAVQEALVPAACSPIDFERDQPEMSFSVRLG 207
            | .||..||  .|.:.|.:.|.|:    .|.|....      |::...:      |:...|..:|
Worm   150 FEITEMYLA--HLLKIPSIPIKSSVRYPAFNNAFGQ------PSSLGYL------PQQGLSREIG 200

  Fly   208 NIRTCIARRKQFIKDHY---GGQEQL-------VTKYFQLQSSIPE----LQASQLSVLLLNSHV 258
            .:...:.     :.|||   ..||:|       :.|  .|...:|.    ::.|.:.:...|.::
Worm   201 FLDRLLE-----VYDHYFLVKMQERLNEYQVNFIEK--ALGHPVPHWRDLVKESPIYITNSNPYL 258

  Fly   259 PLITPKVSIQQIIPAGGL-----HIRGPKELPWNVKRFLEEARPGAIYVQLGN-EQACGQLPKEK 317
            ....|..:  .::..||:     .::.|::||...:..|:| |...:.:..|: .::|......|
Worm   259 DFAVPTTA--TVVHVGGITMDMKKLKNPQQLPDEYEEILQE-RDSTVLISFGSVVRSCDMPENFK 320

  Fly   318 LDTLFAFFSARKQSIIWTCH--DVKTLEGLPKNVMIQHAVPQIDILAHPR-VKAFLTNGDLLNLQ 379
            ...:..|.|....:.||...  ||:..:.|||||.::..|||..:||..| ||.|:|:|.|.:..
Worm   321 AGVVKMFESLPDITFIWKYEKDDVEFQKKLPKNVHLKKWVPQPSLLADKRFVKRFVTHGGLGSTM 385

  Fly   380 EGIMRNVPILGLPLFQHEARNMELAVRLGVG-----LQLEEGNVTTES----------------- 422
            |......|.|.:|:|..:..|..:..|.|..     |.|.:|...|::
Worm   386 EVAYTGKPALMVPIFADQFNNANMLARHGGAIPYDKLDLADGEKFTKTVREMVINPKYNDNAKVL 450

  Fly   423 ----LNWAVD-RLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGIS 482
                ||..:| :|.|..|.:.     ::||.:                        ||::...|:
Worm   451 LIILLNQPIDPKLNLMKHLEF-----AMEFPN------------------------LRSQIPEIN 486

  Fly   483 SCQL---HLFDLFVFYAGIATLVVSLLVALSFGGFYIWNKK 520
            :..|   :..|:..|:...|.|.:.|...|.|..|....||
Worm   487 NAGLIGYYYLDIIAFFILFACLALYLFTNLIFKIFRFVPKK 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	106/512 (21%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	114/549 (21%)
ugt-14	NP_504316.1	egt	5..461	CDD:223071	98/464 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000