DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and ugt-23

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001076755.1	Gene:	ugt-23 / 181205	WormBaseID:	WBGene00007650	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	562	Identity:	115/562 - (20%)
Similarity:	217/562 - (38%)	Gaps:	116/562 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILLAILGLALGQISQAAKILV---LFPHVNEGHFAVMRTLVTELANREHTIEVY----------- 59
            :|.|:|...|..:|...||||   ||.|   .|...:.::|..|.:..|.:.|.
Worm     3 LLSALLLQILFNVSSPYKILVYSNLFGH---SHIKFVGSVVDTLVDAGHDVTVVLPVIDSTQKNR 64

  Fly    60 --TGHGLGESLDNVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFL 122
              ...|..:.:.:..|.|...|   |:.:|..:        .:..:|.....:..:..|.|....
Worm    65 TSIKSGAKQIIIDADEEVVEIF---SQTEKFLS--------NMWTMEMSNPLMMWMNPRILTQLF 118

  Fly   123 AQEPIQKLLKMSYL-------EFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQ 180
            .:: ..|::|:|.|       :||..:       |||..:.|       .||.     .|:.
Worm   119 GKQ-CTKVMKLSELLDQLKSEKFDLAI-------TEAFDSCG-------YGIF-----EYLQ--- 160

  Fly   181 EALVPA-----ACSPIDFERD---QP---------------EMSFSVRLGNIRTCIARRKQF--I 220
               :||     :|:.:|...|   ||               .|:.:.|..|....:.....|  |
Worm   161 ---IPAHVSILSCARMDHVSDVLGQPIAPSYVPGTQSLYSDRMTMTQRFLNYLQFLNGNSMFSDI 222

  Fly   221 KDHYGGQEQLVTKYFQLQSS----IPELQASQLSVLLLNSHVPLIT-PKVSIQQIIPAGGLHIRG 280
            .|:.....:   |...::.|    :||      |..||.:|:|::. |..:..:|:|.||:.:..
Worm   223 GDYESANAK---KLLGVERSWREILPE------SSFLLTNHIPVLEFPAPTFDKIVPIGGISVNK 278

  Fly   281 PKELPWNVKRFLE---EARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQ-SIIW---TCHD 338
            .|| ...::.:.:   ..|...:.:..|:......:|.|...:|...|..... :.||   ...|
Worm   279 NKE-TLKLEHYFDTMVSMRKKNVIISFGSNIKSMDMPDEYKKSLAELFQLMPDVTFIWKYENLAD 342

  Fly   339 VKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMEL 403
            .|...|: .|:.....:||.::||..||.||:|:|.|.::.|......|.:.:|:|..:.||.|:
Worm   343 KKYTCGI-MNINRVEWIPQTELLADSRVDAFITHGGLGSVTELATMGKPAVVIPIFADQTRNAEM 406

  Fly   404 AVRLGVGLQLEEGNVTT-ESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVAR 467
            ..|.|....|.:.::.. |:|...:.:::.:..::...:.::....::|.....:.:..|.:.||
Worm   407 LKRHGGAEVLHKTDLANPETLRKTLRKVMDDPSYRQNAQRLAEMLNNQPTNPKETLVKHVEFAAR 471

  Fly   468 HKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSLLVAL 509
            .....::...|...:..:.:..|:.    .|||::::|:|.|
Worm   472 FGKLPSMDPYGRHQNIIEYYNLDIL----AIATILLTLVVYL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	103/515 (20%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	110/546 (20%)
ugt-23	NP_001076755.1	UDPGT	20..526	CDD:278624	110/545 (20%)
ugt-23	NP_001076755.1	Glycosyltransferase_GTB_type	40..474	CDD:299143	94/481 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	161	1.000	Domainoid score	I2438
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960