DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt317A1 and ugt-58

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_496059.2	Gene:	ugt-58 / 174507	WormBaseID:	WBGene00009450	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	537	Identity:	115/537 - (21%)
Similarity:	214/537 - (39%)	Gaps:	77/537 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVT 72
            |:||  || .:|.:: |..:|.:...:...|...|..|..|||.|.|.:   |...:|....::.
Worm     4 WLLL--LG-TIGWVT-AGDVLFIPSTLYPVHAQTMSVLARELAERGHKV---TWLEIGPERSDIV 61

  Fly    73 --ETVTAEFPFW---------------------SELQKQAAPKGNLADLGLLPIEKLRQSLASVG 114
              :.|:.|  ||                     |||........|         |:....|||:
Worm    62 LHQQVSRE--FWPAQFGDRTLQEIYQFKNHTSHSELWNPQYTNEN---------EQTTGWLASI- 114

  Fly   115 ARALDHFLAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAV 179
             |..|..|::.. .|..||  :|..|..::||..|....:.:..|.:...:....|.........
Worm   115 -RLCDSVLSRSK-SKFDKM--VEKQFSTVIVDDLYNSCGVLMAGLKKSVYIYWSMTGLRTESAWA 175

  Fly   180 QEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQ--EQLVTKYFQLQSSIP 242
            .::..|.:..|:.......:::||.||.|:.:..  ::.:|..|....  :.:..||:....|..
Worm   176 NQSPSPPSYLPVAGTGLTDDLTFSQRLYNVASYF--KQLYIHQHIVQPRIDAVFQKYYPGVESTF 238

  Fly   243 ELQASQLSVLLLNSHVPLI------TPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEARPGAIY 301
            |::.: .|:..:|: .|:.      .|:|:.     .|.:..|.|||||.....::.....|.:.
Worm   239 EIERN-ASINFVNT-PPIFDFSRPYMPRVNF-----IGAIQCRKPKELPKEFTSWISAYPDGFVV 296

  Fly   302 VQLGNEQACGQLPKE----KLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILA 362
            :..|......:.|:.    .|||   |........||.. .:.....||.|::::..:|..|:|.
Worm   297 LSTGFTVQWNKSPEHIRQAYLDT---FKYLPNLLFIWQT-GLPNSSNLPSNLLVKPWLPLQDLLG 357

  Fly   363 HPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAV 427
            |.:.:..:::|.|.::.|.:...||::|:||......|:........|:.:|:...:.|.|..|:
Worm   358 HQKCRCHVSHGGLNSVIESVYHGVPVVGVPLTSRGYDNLLRITARDSGVMVEKSEFSGEILTAAI 422

  Fly   428 DRLLLESHFQ---LTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLF 489
            :.::....::   |..:|:.:   |.|...|..|.|||.::.||:.....|:....::..|..|.
Worm   423 NEVIENEKYKKEMLIFQDMVI---DVPYTELYHAAFWVEFIERHQEVPHARSGADHLNFLQYFLV 484

  Fly   490 DLFVFYAGIATLVVSLL 506
            |:..|:..:....:|::
Worm   485 DVIAFFFFVIFCTLSII 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	104/492 (21%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	108/520 (21%)
ugt-58	NP_496059.2	UDPGT	17..485	CDD:278624	105/502 (21%)
ugt-58	NP_496059.2	Glycosyltransferase_GTB_type	<200..462	CDD:299143	60/277 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810