DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt317A1 and ugt-26

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_491435.2	Gene:	ugt-26 / 172085	WormBaseID:	WBGene00015695	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	539	Identity:	110/539 - (20%)
Similarity:	215/539 - (39%)	Gaps:	73/539 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVTE 73
            ::|..|.|.     .:..|||..|.....|...|..|...|....|.:.......|.|..|.:..
Worm    11 LVLCTLSLV-----SSLNILVHSPAYAASHTNFMARLADTLTEAGHNVTFLVPIALEERRDKLGV 70

  Fly    74 TVTAEFPFW---SELQKQAAP-KGNLADLGLLPIEKLRQSLASVGAR----------ALDHFLAQ 124
            .:|.:....   .|::.:..| .|::..|.::.::.     :|:.|.          ..::|:..
Worm    71 KLTKDVIIVEQDEEMKSKLVPHSGSIEFLWIIEMDS-----SSIDAMFSWYNEIMILTCENFMRN 130

  Fly   125 EPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPV-VGIISTDFGNYMDAVQEALVPAAC 188
            :.:...||..:    |||.:.:.|   .:..||...:..: ..|:.:...:|     :.::|...
Worm   131 KQVMSELKSRH----FDVAIAEPF---TICGLGLFEELNIKKTILVSSCAHY-----DFMLPHIG 183

  Fly   189 SPIDF-------ERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPELQ- 245
            .|.||       .:...|||.:.:..|.| .:|..|..:...:..:.::..:.|  .|.||:.:
Worm   184 EPEDFSSVPTLSSKVGEEMSMTEKWENYR-LVAETKASLAKLFDAETRIYRESF--GSDIPDWKE 245

  Fly   246 -ASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEA---RPGAIYVQLGN 306
             .|..|:...||:..:..|:.|||:.|..||:.:...:.....:.:..||.   |..::.:..|:
Worm   246 LMSSASLYFTNSNPFIDYPRASIQKTISIGGITVDFQQIKSEKLNKEWEEVLNKRQKSMLISFGS 310

  Fly   307 EQACGQLPKEKLDTLF--AFFSARKQ----SIIW--TCHDVKTLEGLPKNVMIQHAVPQIDILAH 363
                 .:|.:|:...:  ..|...|.    :.||  ...||...:|: .|:.....|||..:|..
Worm   311 -----NVPSDKMPAAWKAGIFETIKSMPNVTFIWKYESDDVSFADGI-SNIHFSKWVPQTALLND 369

  Fly   364 PRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQL---EEGNVTTESLNW 425
            ||:.||||:|.|.:..|......|.:.:|::..:.||..:..|.|..:.|   |..||  :.:..
Worm   370 PRLSAFLTHGGLGSTNELAYCAKPAVMVPIYGDQTRNANMLARHGSVIVLHKKELANV--QRVKK 432

  Fly   426 AVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFD 490
            ||..:|....:..:...::...:::|.....:.:.:..:||::.....:...|..::..|....|
Worm   433 AVHDILYNKQYTESAERIAEMIKNQPKTPKETVVRYTEFVAKYGPFPQMAPHGRKLTYFQKTFLD 497

  Fly   491 LFVFYA--GIATLVVSLLV 507
            ::..:|  .::.|.|:.||
Worm   498 IYSLFALGVVSVLTVAFLV 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	99/492 (20%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	107/523 (20%)
ugt-26	NP_491435.2	egt	4..481	CDD:223071	102/502 (20%)
ugt-26	NP_491435.2	UDPGT	34..525	CDD:278624	103/511 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960