Protein Alignment Ugt317A1 and Ugt1a6

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_476446.2
• Gene: Ugt1a6 / 113992
• RGDID: 620949
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 135/562 - (24%)
• Similarity: 231/562 - (41%)
• Gaps: 90/562 - (16%)

  Fly     8 WILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHG---LGESLD 69
            ::.|.:.|..||.     |:||: |. :..|:..|:.:|..|:.|.|.|.|.....   ||||
  Rat    14 FLFLVLWGSVLGD-----KLLVV-PQ-DGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGES-- 69

  Fly    70 NVTETVTAEFPFWSELQKQAAPKGNLADLGLLP--IEKLRQSLASVGARALDHFLAQEPIQKLLK 132
                         ...::::.|         :|  :|:||....|.|.   :||.|..|:...|:
  Rat    70 -------------KYYRRKSFP---------VPYNLEELRTRYRSFGN---NHFAASSPLMAPLR 109

  Fly   133 MSYLEFDFDVILVD--YFYTEALL------------ALGALHQRPVV--GIISTD---------F 172
                |:..::|::|  :|..::||            ...||...|.:  |:|..:         |
  Rat   110 ----EYRNNMIVIDMCFFSCQSLLKDSATLSFLRENQFDALFTDPAMPCGVILAEYLKLPSVYLF 170

  Fly   173 GNYMDAVQEAL----VPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDH--YGGQEQLV 231
            ..:..:::..|    .|.:..|..:.:....|:|..||.|.   ||...:....|  |...|.|.
  Rat   171 RGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANF---IANILENYLYHCLYSKYEILA 232

  Fly   232 TKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLE-EA 295
            :...:...|:|.|.  |.|:.||........|:..:..:|..||.:.:....|....:.::. ..
  Rat   233 SDLLKRDVSLPALH--QNSLWLLRYDFVFEYPRPVMPNMIFIGGTNCKKKGNLSQEFEAYVNASG 295

  Fly   296 RPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDI 360
            ..|.:...||:  ...::|::|...:........|:::|.....:. ..|.||.::...:||.|:
  Rat   296 EHGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRP-SNLAKNTILVKWLPQNDL 357

  Fly   361 LAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNW 425
            |.||:.:||:|:.....:.|||...||::.:|||..:..|.:.....|.|:.|....:|.:.|..
  Rat   358 LGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLEN 422

  Fly   426 AVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFD 490
            |:..::....::..|..:|...:|||:..|..|:|||.||.||||...||.....::..|.|..|
  Rat   423 ALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLD 487

  Fly   491 LFVFYAGIATLVVSLL-------VALSFGGFYIWNKKNNSKS 525
            :..|...|...||.::       ....|||.....|.:.||:
  Rat   488 VIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	100/442 (23%)
Ugt1a6	NP_476446.2	UDPGT	26..521	CDD:278624	128/540 (24%)