Protein Alignment Ugt317A1 and Ugt2b38

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_598655.1
• Gene: Ugt2b38 / 100559
• MGIID: 2140794
• Length: 530
• Species: Mus musculus
• Alignment Length: 565
• Identity: 135/565 - (23%)
• Similarity: 236/565 - (41%)
• Gaps: 85/565 - (15%)

  Fly     1 MESQWNRWILLAILGLALGQIS------QAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVY 59
            |..:|       |..|.|.|||      :..|:|| :| :...|:..::.::.||..|.|.:.|.
Mouse     1 MPGKW-------ISALLLLQISCCFRSVKCGKVLV-WP-MEFSHWMNIKIILDELVQRGHEVTVL 56

  Fly    60 -----------TGHGL-------GESLDNVTETVTAEFPFWS-ELQKQAAPKGNLADLGLLPIEK 105
                       ...||       ..|.||:..........|: |:.:...          |....
Mouse    57 RPSAYYVLDPKKSPGLKFETFPTSVSKDNLENFFIKFVDVWTYEMPRDTC----------LSYSP 111

  Fly   106 LRQSLASVGARALDHF------LAQEPI-QKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRP 163
            |.|::       :|.|      |.::.: .|.|.....|..|||:|.|...:...| :..|.|.|
Mouse   112 LLQNM-------IDEFSDYFLSLCKDVVSNKELMTKLQESKFDVLLSDPVASCGEL-IAELLQIP 168

  Fly   164 VVGIISTDFGNYMD-AVQEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRK-----QFIKD 222
            .:..|....|..:: :....|:|.:..|:.......:|:|..|:.|:   |.|..     |...|
Mouse   169 FLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGLGGQMTFIERVKNM---ICRLYFDFWFQMFND 230

  Fly   223 HYGGQEQLVTKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWN 287
            .  ..:...::|....:::.|.. .:..:.|:.|:..|..|..::..:...||||.:..|.||.:
Mouse   231 K--KWDSFYSEYLGRPTTLAETM-GKAEMWLIRSNWDLEFPHPTLPNVDYVGGLHCKPAKPLPKD 292

  Fly   288 VKRFLEEARP-GAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMI 351
            ::.|::.:.. |.:...||:  ....:.:||.:|:....:...|.::|. .|.||...|..|..:
Mouse   293 MEEFVQSSGDHGVVVFSLGS--MVSNMTEEKANTIAWALAQIPQKVLWK-FDGKTPATLGHNTRV 354

  Fly   352 QHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEG 416
            ...:||.|:|.||:.|||:|:|....:.|.|...:|::|:|||..:..|:...|..|..:.|
Mouse   355 YKWLPQNDLLGHPKTKAFVTHGGANGVYEVIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVTL--- 416

  Fly   417 NVTTES----LNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTR 477
            |:.|.|    || |::.::....::.....:|....|:|...|..|:|||.:|.|||....||:.
Mouse   417 NIRTMSRSDVLN-ALEEVIDNPFYKKNAIWLSTIHHDQPTKPLDRAVFWVEFVMRHKRAKHLRSL 480

  Fly   478 GIGISSCQLHLFDL--FVFYAGIATLVVSLLVALSFGGFYIWNKK 520
            |..::..|.|..|:  |:......|:|:::...|....|::..:|
Mouse   481 GHNLTWHQYHFLDVIGFLLSCVAVTIVLTVKCLLFIYRFFVKKEK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	103/442 (23%)
Ugt2b38	NP_598655.1	UDPGT	24..526	CDD:278624	127/535 (24%)