Protein Alignment Ugt317A1 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 546
• Identity: 136/546 - (24%)
• Similarity: 235/546 - (43%)
• Gaps: 47/546 - (8%)

  Fly     4 QWNRWILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHG---LG 65
            :::.:.:.|:|.|...|:.:|.|:|.:  .::..|:..||.||..|..|.:.:.|...|.   :.
 Frog     8 EYSVYRVFALLFLGRVQLIEAEKLLAI--PLDGSHWLSMRILVESLGQRGNQVVVLAPHSNIHIH 70

  Fly    66 ESLDNVTETVTAEFPFWSELQKQAAPKG--------NLADLGLLPIEKLRQSLASVGA---RALD 119
            .|.:.:..|...  |:..||.|:...|.        .|.|    .|..:.|.:.:|..   .|..
 Frog    71 PSENYILRTYPV--PYSKELLKEQMVKSANDVFTKRPLLD----KITNMYQRITNVTGIVFSACQ 129

  Fly   120 HFLAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALV 184
            |.|..:.|.:.|:    |..||..|:|.|:...::....||...|..:.....|....|.| ...
 Frog   130 HLLHSKEIMQELQ----ESAFDAALIDPFFPCGMIVAEYLHLPSVYLLYGLPCGIDRLATQ-CPS 189

  Fly   185 PAACSPIDFERDQPEMSFSVRLGN-----IRTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPEL 244
            |.:..|..|..:...|||..||.|     :.|.:....      |....||.:::...:.:|.:|
 Frog   190 PLSYVPRHFTGNTDHMSFPQRLKNALLWPVDTFLCNLL------YSPYAQLASEFLHREMTILQL 248

  Fly   245 QASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEA-RPGAIYVQLGNEQ 308
            . ||.||.|:.:......|:..:..::..||::..|.:.|....::.:..: ..|.:...||:
 Frog   249 Y-SQTSVWLMKTDFVFDYPRPLMPNMVFVGGINCVGEQHLNQEFEKLVNSSGEHGFVVFSLGS-- 310

  Fly   309 ACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNG 373
            ...::|..|...:.....:..|.:.|. :..|....|.:|..:...:||.|:||||:.:||:|:.
 Frog   311 MVSEIPMNKAMDIAEALKSIPQKVFWR-YTGKAPPNLGENTHLVKWLPQNDLLAHPKARAFITHA 374

  Fly   374 DLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQL 438
            ....:.|||...||::.:|||..:..|.:.....|.||.|...::|.|.|:.||..::....::.
 Frog   375 GSHGIYEGICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVRAVINNPVYKE 439

  Fly   439 TIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVV 503
            .|:.:|....|||:..|..|:.||.:|.||||...||.....::..|.:..|:..|.  :|.|:.
 Frog   440 NIQRMSSLHLDRPIHPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYYSLDVIGFL--LAVLLT 502

  Fly   504 SLLVALSFGGFYIWN--KKNNSKSTK 527
            :|.::|....|....  |:|:.|..|
 Frog   503 ALFISLKCCTFVFRRCFKRNSKKQRK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	103/425 (24%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	129/519 (25%)