DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	541	Identity:	142/541 - (26%)
Similarity:	235/541 - (43%)	Gaps:	86/541 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILLAILGLALGQISQAAKILVLFPHVNEG-HFAVMRTLVTELANREHTIEVYTGHGLGESLDN-- 70
            :.:.:|.|.|.  ....|||| |||  || |:..:.||:.||.:|.|.|.|.      .:||:
Zfish    38 VQIVVLSLTLP--VHCGKILV-FPH--EGSHWLNLNTLIEELHHRGHQISVI------RALDSWY 91

  Fly    71 VTETV----TAEFPF-------------WSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARAL 118
            :.||.    :...||             :.:||.:...:.....|.:    :|::..:.:..:..
Zfish    92 IPETSPHYDSINVPFLLGGDDQFYHSFIFRQLQIRREQRWTRFKLDM----ELKEKFSEMHRKIC 152

  Fly   119 D---HFLAQEP-IQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAV 179
            :   |.:.:|| |.|.:|    |.:||::|.|......::....||...|..:..|..|.    .
Zfish   153 EMVIHIVEKEPAIMKQIK----EANFDIMLTDPANGGGVVLAHYLHLPLVFNVQWTVHGE----A 209

  Fly   180 QEALVPAACSPIDFERDQ--PEMSFSVRLGN-----IRTCIARRKQFIKDHYGGQEQLVTK---- 233
            ..|:.|:..|.:.|...|  ..|||..|:.|     :|..:.||.  :..||..   |..:
Zfish   210 HFAIAPSPPSYVPFPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRT--VGPHYSA---LCNRLFGP 269

  Fly   234 ---YFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEA 295
               ||:|      .||:  .:.|:.:......|:.::..:|..||.|....|.||.:::.||:.:
Zfish   270 GLDYFEL------FQAA--DIWLMRADFVFDFPRPTMPNVIYIGGFHCSPAKALPKDLEDFLQSS 326

  Fly   296 -RPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNV----MIQHAV 355
             ..|.|.:.||...|  |||.:..|.:.|.|:...|.:||     :.....|.||    ::.:.:
Zfish   327 GEHGVIVMSLGTLVA--QLPMDIADEIVAAFAELPQKVIW-----RYTGDRPANVGNNTLLVNWL 384

  Fly   356 PQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTT 420
            ||.|:|.||:.:.|:::|....:.|.|...|||:||||...:..|:......||...|:...:..
Zfish   385 PQNDLLGHPKTRVFVSHGGTNGVFEAIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINR 449

  Fly   421 ESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQ 485
            .....|:..:|.:..::..::.:|...:|.||..|.|||||..:|.||:|.:.|||....:....
Zfish   450 NIFKDALQEVLNDPSYRSNMQKLSSLHKDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYS 514

  Fly   486 LHLFDLFVFYAGIATLVVSLL 506
            .|..|:.||...:...:|.|:
Zfish   515 YHSVDVGVFLVSVLCFIVFLM 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	132/497 (27%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	139/525 (26%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910