DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt317A1 and ugt5a4

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001170969.2	Gene:	ugt5a4 / 100415798	ZFINID:	ZDB-GENE-100406-1	Length:	525	Species:	Danio rerio

Alignment Length:	538	Identity:	133/538 - (24%)
Similarity:	230/538 - (42%)	Gaps:	85/538 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEV-------------- 58
            ::||.:|..     |.|.|:||:  .|:..|:..|:.|:.||.::.|:|.|
Zfish    11 FLLLCVLSR-----SHAGKLLVV--PVDGSHWINMKVLLVELHSKGHSITVVRASNSWYIEEQSP 68

  Fly    59 -YTG----HG-----LGES-LDNVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLAS 112
             ||.    :|     .||. |.::.:.......||:|:.        |||.......::.|.:..
Zfish    69 LYTSITVENGEFDADFGEKFLPHLLKMQRQGKSFWTEMA--------LADETYSRFTEIHQEICK 125

  Fly   113 VGARALDHFLAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMD 177
            :.|...::    |.:...||    :..:||:|.|..:...:|....|....|..:..|.:|
Zfish   126 MTATMFEN----ETLMNSLK----DAAYDVVLTDPAFGGGVLLAHRLGLPLVFNVRWTMYG---- 178

  Fly   178 AVQEALVPAACSPIDFE-----RDQPEMSFSVRLGNIRTCIA---RRKQFIKDHYGGQEQLVTKY 234
               ||....|.||:.:.     :...:|:||.|:.|:.|.|.   :..::....|   ::|..||
Zfish   179 ---EAHFVIAPSPLSYVPVSGLQLTDKMTFSQRVMNMMTYIMILYKNSKYFGSPY---QELTQKY 237

  Fly   235 FQLQSSIPELQASQL----SVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEA 295
            |.     |.:....|    .:.|:.:......|:.::..::..||...:..|.||.:::.|::.:
Zfish   238 FG-----PNVNFFSLLQDADLWLMRNDFTFEFPRPTMPNVVYMGGFQCKPAKPLPGDLEEFVQSS 297

  Fly   296 -RPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQID 359
             ..|.|.:.||  ...|||..|..|.:.|.|:...|.:||.....:. ..|..|.:|.:.:||.|
Zfish   298 GEHGVIMMSLG--AVFGQLLSELNDEIAAAFAQLPQKVIWRYTGPRP-ANLGNNSLIVNWLPQND 359

  Fly   360 ILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLN 424
            :|.||:.|.|:.:|....|||.|...|||:||||...:..|:......|....::...:......
Zfish   360 LLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFDQPDNLSRMRAKGTAKIVDIATLDRAVFL 424

  Fly   425 WAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLF 489
            .|:..:|....::..::.:|....|:|:..|..|:||:.:|.|:||...|||:...:|..:....
Zfish   425 EALKEVLHNPSYRENMQRLSKLHHDQPMKPLDRAIFWIEFVMRNKGAPHLRTQSFRMSWIEYQSI 489

  Fly   490 DLFVFYAGIATLVVSLLV 507
            |:      |.||:|.:||
Zfish   490 DV------ILTLMVMVLV 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	121/492 (25%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	128/521 (25%)
ugt5a4	NP_001170969.2	UDPGT	23..525	CDD:278624	128/521 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000