Protein Alignment Ugt317A1 and ugt1b3

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001170817.1
• Gene: ugt1b3 / 100384903
• ZFINID: ZDB-GENE-080227-12
• Length: 535
• Species: Danio rerio
• Alignment Length: 555
• Identity: 134/555 - (24%)
• Similarity: 228/555 - (41%)
• Gaps: 108/555 - (19%)

  Fly    13 ILGLALGQISQAA-------------KILVLFPHVNEGHFAVMRTLVTELANREHTIEVY---TG 61
            |..|.:|.:..||             |:||:  .::..|:..::.:..|:..|.||:.|.   ..
Zfish    10 IFCLVVGVVCSAAVDQKLSRKSSWTGKLLVV--PMDGSHWTGVKAVAEEMGRRGHTVIVVIPEIS 72

  Fly    62 HGLGESLDNVTETVTAEF------------------PFWSELQKQAAPKGNLADLGLLPIEKLRQ 108
            ..||.....:|:....::                  |..|.|:...:...||.        |:..
Zfish    73 MRLGPGKHYITKKFPVKYDQKLFNEVLTEHVHEVTNPGHSRLKTVTSTMANLL--------KMFN 129

  Fly   109 SLASVGARALDHFLAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFG 173
            .:||..    :.....:.:.|.|:    :.:||.||     |:..|.:||        :::.:|.
Zfish   130 MMASTS----ESLFQDKELIKFLR----DENFDAIL-----TDPALPMGA--------VLAYNFS 173

  Fly   174 NYMDAVQEALVPA----------------AC--SPIDFER----DQPEMSFSVRLGNIRTCIARR 216
                      |||                ||  :|....|    :...|||..|:.|:...|..:
Zfish   174 ----------VPAVYMLRGMPCALDATATACPNTPSYIPRFHTGNTDRMSFGERVMNVLMSILEQ 228

  Fly   217 KQFIKDHYGGQEQLVTKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGP 281
            .. .|..|...|::...:.|...|:.|: .|..:|.|:.....|..||..:..:...||::....
Zfish   229 VA-CKVMYWSFEEVTPNFLQRDVSLTEI-LSTGAVWLMRYDFTLEFPKPLMPNMQFIGGINCGVK 291

  Fly   282 KELPWNVKRFLE-EARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGL 345
            ..|...|:.|:. ....|.:...||:  ....:||||.|..|..||...|.::|. :..:....:
Zfish   292 NPLMKEVEEFVNGSGEHGIVVFSLGS--LVSSMPKEKADIFFKAFSMIPQRVLWR-YTGEIPNNV 353

  Fly   346 PKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVG 410
            |:||.:...:||.|:|..|:.:||:|:|....:.|||...||::.||||..:|.|:......|||
Zfish   354 PENVKLMKWLPQNDLLGPPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVG 418

  Fly   411 LQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALR 475
            :.|...::|.|:|..|::.::..|.::..::.:|....|||:..|..|:||..:|.||||...||
Zfish   419 VILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLR 483

  Fly   476 TRGIGISSCQLHLFDLFVFYAGIATLVVSLLVALS 510
            .....::..|.|..|:..|     .|::.|:|.|:
Zfish   484 PAAHELNWLQYHSLDVIGF-----MLLIVLIVTLA 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	106/462 (23%)
ugt1b3	NP_001170817.1	UDPGT	35..516	CDD:278624	129/530 (24%)