Protein Alignment Ugt317A1 and ugt2a3

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001170814.2
• Gene: ugt2a3 / 100384900
• ZFINID: ZDB-GENE-080721-22
• Length: 532
• Species: Danio rerio
• Alignment Length: 541
• Identity: 121/541 - (22%)
• Similarity: 219/541 - (40%)
• Gaps: 83/541 - (15%)

  Fly    10 LLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVTET 74
            ||..|.|....:..:.::||:....:  |:..||.::..|.:|.|::.|.    :|.|...|..|
Zfish     6 LLVCLLLCGVDVGWSGRVLVMPGEYS--HWHNMRAIIEALVDRNHSVTVL----VGSSSPTVPHT 64

  Fly    75 VTAEFPF---------------WSEL----QKQAAPKGNLADLGLLPIEKLRQSLASVGARALDH 120
            ..|.|.:               ||:.    ..:.|.|              .:::::: .:.:..
Zfish    65 QKARFDYHVFKVNIEKEEADAVWSDFIYLWMNETATK--------------YETVSNI-FQVMSR 114

  Fly   121 FLA----------QEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNY 175
            |:.          :|.:.::|:.|:    :||:..|.....:.|....|:...|:.:.:|...::
Zfish   115 FMTLTDEVCKGMFKEDLLQMLRESH----YDVLFSDPMMPCSDLMAQTLNIPLVLSLRATFAYSF 175

  Fly   176 MDAVQEALVPAACSPIDFERDQ--PEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKY--FQ 236
            .....:...|.:..|....||.  ..|||..|:.|:..            |...:.....|  |.
Zfish   176 ERMCGQMPAPPSYVPAASLRDHLTDRMSFMERVENMLL------------YFSHDVFFKLYMMFT 228

  Fly   237 LQSSIPELQA---------SQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFL 292
            ......|::.         .:..:.|:.::.....|:.........||||.:..|.|...::.|:
Zfish   229 FDRIYTEIRGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFV 293

  Fly   293 EEARP-GAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVP 356
            :.:.. |.:...||:  ....|..|:.:|:.|......|.::|. :..||.|.|..|..|...:|
Zfish   294 QSSGDHGVVVFSLGS--MIKNLTSERANTIAAALGQIPQKVVWR-YSGKTPETLAPNTKIYDWIP 355

  Fly   357 QIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTE 421
            |.|:|.||:.|||:|:|....|.|.|...||::|||||..:..|:......|..:.|:...:.::
Zfish   356 QNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESK 420

  Fly   422 SLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQL 486
            .|..|:..:|....::.:|..:|....|:|:..|..|::|:.:|.|:||...||.:...:|..|.
Zfish   421 DLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQY 485

  Fly   487 HLFDLFVFYAGIATLVVSLLV 507
            |..|:..|...||.|:..|.|
Zfish   486 HCLDVAAFLLSIAALITFLWV 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	93/448 (21%)
ugt2a3	NP_001170814.2	UDPGT	21..519	CDD:278624	117/526 (22%)