Protein Alignment Ugt317A1 and ugt2b3

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001170812.2
• Gene: ugt2b3 / 100384898
• ZFINID: ZDB-GENE-100402-2
• Length: 527
• Species: Danio rerio
• Alignment Length: 545
• Identity: 131/545 - (24%)
• Similarity: 228/545 - (41%)
• Gaps: 66/545 - (12%)

  Fly    16 LALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGL---------GESLDNV 71
            |.:....|...|||.  |....|:..::.::..|.:|.|.:.|....|.         ..|..|.
Zfish    11 LTVFSAGQCGNILVW--HTEGSHWINLKIVLDTLLDRGHNVTVLMPDGALFMKAKESDRFSYQNF 73

  Fly    72 TETVTAE--FPFWSELQKQAAPKGNLADLGLLPIEKLRQSLAS----VGARALDHFLAQEPIQKL 130
            :.:.:|:  ..|..||...:.  ..:..|.||.|:.....|.|    :|....|..|....:...
Zfish    74 SVSTSAQDMQDFLDELLHFSV--FEMEQLNLLQIQMKFFDLGSRHQDMGLSYCDGILKSPELMDK 136

  Fly   131 LKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAV------QEALVPAACS 189
            ||..    .|||:|.|..|..:.:....|:. |:|..:.....:.|:.:      ..:.||.|.|
Zfish   137 LKTG----KFDVLLSDPMYPCSDIVAEVLNV-PLVFTLRFSIAHTMERICGQIPAPPSYVPGAMS 196

  Fly   190 PIDFERDQPEMSFSVRLGNI-------RTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPELQAS 247
            .:     ..:|||:.|:.|.       ...|...|:|  |:|      .|:||...:|..|:. .
Zfish   197 KL-----TDKMSFTERIFNTLFYLSMDTFSIIAWKKF--DNY------YTEYFGRPTSYCEMM-G 247

  Fly   248 QLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEA-RPGAIYVQLGNEQACG 311
            :..:.|:.::.....|:..:......||||....|.||.:::.|::.: ..|.:...||:  ...
Zfish   248 RADIWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQSSGDDGIVVFTLGS--MID 310

  Fly   312 QLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLL 376
            ::|||..:.:.:..:...|.::|.....|. :.|.:|..|...:||.|:|.||:.:||:|:|...
Zfish   311 KVPKEMSNRIASALAQIPQKVLWRYGGEKP-DTLGENTRIYKWMPQNDLLGHPKTRAFITHGGTN 374

  Fly   377 NLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRL---LLESHFQL 438
            .:.|.|...||::|:|||..:..||......|..:.::  ::.:......||:|   :.:..::.
Zfish   375 GIYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVD--SIKSMQPQELVDKLNTVINDPSYKE 437

  Fly   439 TIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVV 503
            ....:|....|||:..|..::||:.:|.|:||...||.....::..|.|..|:|.|...:.|||
Zfish   438 NAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLV- 501

  Fly   504 SLLVALSFGGFYI----WNKKNNSK 524
             |.:......|:|    :..|..||
Zfish   502 -LYICFKMAKFFIMRCCFRSKRKSK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	102/437 (23%)
ugt2b3	NP_001170812.2	UDPGT	20..523	CDD:278624	127/532 (24%)