Protein Alignment Ugt317A1 and ugt2a1

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001177979.1
• Gene: ugt2a1 / 100006320
• ZFINID: ZDB-GENE-080721-20
• Length: 539
• Species: Danio rerio
• Alignment Length: 546
• Identity: 136/546 - (24%)
• Similarity: 226/546 - (41%)
• Gaps: 88/546 - (16%)

  Fly     8 WILLAILGLALGQ---ISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESL- 68
            ::|||:|   |.|   .....|||| :| ....|:..::.::..|..|.|.|.|.| |....|:
Zfish    10 FLLLALL---LNQNLLCVSGGKILV-WP-AEFSHWLNIKVILDVLIERGHNITVVT-HTATPSVQ 68

  Fly    69 ------------------DNVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGA 115
                              ..:.:.:.....:|:    ...|..|:....|    |:.:.:.:..|
Zfish    69 TTPSAGYNAEILQVPYTKQEIVDNLERMLKYWT----HDLPNDNIITASL----KIHEMITTATA 125

  Fly   116 R---ALDHFLAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQR---PVVGIISTDFGN 174
            :   ..:...::..:.:..||.    .|||||.|..|    :....|.|:   |::..:...|||
Zfish   126 QNKITCNALFSRADLLEKWKME----KFDVILADPLY----ICGEILAQKLDIPLIFSLRFTFGN 182

  Fly   175 YMDAV------QEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQE---QL 230
            .::.:      ..:.|||..|.   :.||  |.|          |.|.|.|:  .||.|:   .|
Zfish   183 TLERLCGQMPAPPSYVPAVASE---KTDQ--MDF----------IDRLKNFL--FYGMQDFLFYL 230

  Fly   231 VTK-----YFQLQSSIPELQASQL---SVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWN 287
            |||     |:......|......:   .:.|:.::.....|:.........||||.:..|.|...
Zfish   231 VTKFKWDHYYSEVLGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKE 295

  Fly   288 VKRFLEEARP-GAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMI 351
            ::.|::.:.. |.:...||:  ....|..|:.:|:.|......|.::|. :..||.|.|..|..|
Zfish   296 MEEFVQSSGDHGVVVFSLGS--MIKNLTSERANTIAAALGQIPQKVVWR-YSGKTPETLAPNTKI 357

  Fly   352 QHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEG 416
            ...:||.|:|.||:.|||:|:|....|.|.|...||::|||||..:..|:......|..:.|:..
Zfish   358 YDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDIN 422

  Fly   417 NVTTESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGI 481
            .:.::.|..|:..:|....::.:|..:|....|:|:..|..|::|:.:|.|:||...||.:...:
Zfish   423 TLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHEL 487

  Fly   482 SSCQLHLFDLFVFYAGIATLVVSLLV 507
            |..|.|..|:..|...||.|:..|.|
Zfish   488 SWYQYHCLDVAAFLLSIAALITFLWV 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	106/448 (24%)
ugt2a1	NP_001177979.1	UDPGT	27..526	CDD:278624	130/526 (25%)