Protein Alignment CG3732 and ZRANB2

DIOPT Version :9

• Sequence 1: NP_611692.1
• Gene: CG3732 / 37588
• FlyBaseID: FBgn0034750
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_976225.1
• Gene: ZRANB2 / 9406
• HGNCID: 13058
• Length: 330
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 127/277 - (45%)
• Similarity: 162/277 - (58%)
• Gaps: 52/277 - (18%)

  Fly    20 SPGDWICPDYDCRHLNFARRLQCNKCDRDRDGSDKPERDRDRDRERERGNGSSSSSSSSSKKKLG 84
            |.|||||||..|.::|||||..||:|.|::                        ::.:...|..|
Human     9 SDGDWICPDKKCGNVNFARRTSCNRCGREK------------------------TTEAKMMKAGG 49

  Fly    85 TEIGKAAADKSRGLFSAEDWQCSKCANVNWARRQTCNMCNAPKFSDVEERTGFGGGYNDRGVVEY 149
            |||||..|:||||||||.||||..|:|||||||..|||||.||::.:|||||:|||:|:|..|||
Human    50 TEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEY 114

  Fly   150 KDRQDSDSEYDEFGRRKKRKHG---------EHREDSKRPRRSSRDEQRNDEEE------DEDDD 199
            .:|::||.|||||||:||:..|         :..||     :.|..|:.:::|:      |||:|
Human   115 IEREESDGEYDEFGRKKKKYRGKAVGPASILKEVED-----KESEGEEEDEDEDLSKYKLDEDED 174

  Fly   200 EGDDEDLSKYDLWGDEEVTSTDVKSKEGTGNGDKERKRTSRDSTSSVSSSSSSSSSSSSDSSSSS 264
            | ||.|||||:|...||..|...||       ::..:..||.|.|..||.|||.|||.|.|.|.|
Human   175 E-DDADLSKYNLDASEEEDSNKKKS-------NRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS 231

  Fly   265 SSSSSSGGRRKTSSSGR 281
            .|||||..|.::||..|
Human   232 RSSSSSQSRSRSSSRER 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3732	NP_611692.1	ZnF_RBZ	22..46	CDD:197784	15/23 (65%)
		RanBP2-type Zn finger	24..45	CDD:275376	13/20 (65%)
		zf-RanBP	100..129	CDD:279035	21/28 (75%)
		RanBP2-type Zn finger	104..123	CDD:275376	13/18 (72%)
ZRANB2	NP_976225.1	ZnF_RBZ	11..35	CDD:197784	15/23 (65%)
		RanBP2-type Zn finger	13..34	CDD:275376	13/20 (65%)
		ZnF_RBZ	67..91	CDD:197784	17/23 (74%)
		RanBP2-type Zn finger	69..88	CDD:275376	13/18 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..330		61/145 (42%)
		Required for nuclear targeting	151..324		46/106 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142145
Domainoid	1	1.000	113	1.000	Domainoid score	I6169
eggNOG	1	0.900	-	-		E1_KOG1995
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3538
Isobase	1	0.950	-	0	Normalized mean entropy	S3106
OMA	1	1.010	-	-		QHG60166
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007371
OrthoInspector	1	1.000	-	-		oto88313
orthoMCL	1	0.900	-	-		OOG6_106338
Panther	1	1.100	-	-	LDO	PTHR12999
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3341
SonicParanoid	1	1.000	-	-		X5493
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.740