DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bonsai and MRPS15

DIOPT Version :9

Sequence 1:	NP_611691.1	Gene:	bonsai / 37587	FlyBaseID:	FBgn0026261	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_112570.2	Gene:	MRPS15 / 64960	HGNCID:	14504	Length:	257	Species:	Homo sapiens

Alignment Length:	169	Identity:	57/169 - (33%)
Similarity:	89/169 - (52%)	Gaps:	19/169 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 KPEKSGDLAKLPPLKADELLPEYRDCKELDKADESVKSLFKL--SNNASYLTTKFYRDEMVKEVQ 101
            ||.:| .|...||  ...||.:|::...::|.|:.||.|..|  :|....|  |..:::.:|::.
Human    57 KPAQS-RLDDDPP--PSTLLKDYQNVPGIEKVDDVVKRLLSLEMANKKEML--KIKQEQFMKKIV 116

  Fly   102 RHAQDFGSMEAKLAKMTAVIRRYQEHMDKHPRDKMIKVRLKELIDKRKKFLKYLRRWDYPRFEWI 166
            .:.:|..|:||::..::..||.|:||::||.:||..|..|...||:|||.||.||..:|..||.|
Human   117 ANPEDTRSLEARIIALSVKIRSYEEHLEKHRKDKAHKRYLLMSIDQRKKMLKNLRNTNYDVFEKI 181

  Fly   167 LEKLDLVYKPPP-----THFHWITRK-------ESLQKL 193
            ...|.:.|..||     .|..::|:|       :..|||
Human   182 CWGLGIEYTFPPLYYRRAHRRFVTKKALCIRVFQETQKL 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bonsai	NP_611691.1	Ribosomal_S15	97..172	CDD:278728	30/74 (41%)
MRPS15	NP_112570.2	Ribosomal_S15	112..187	CDD:395247	30/74 (41%)
MRPS15	NP_112570.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	225..257
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143583
Domainoid	1	1.000	58	1.000	Domainoid score	I10837
eggNOG	1	0.900	-	-		E1_COG0184
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1539741at2759
OrthoFinder	1	1.000	-	-		FOG0003129
OrthoInspector	1	1.000	-	-		oto90353
orthoMCL	1	0.900	-	-		OOG6_101240
Panther	1	1.100	-	-	LDO	PTHR46685
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1262
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.740