Protein Alignment Cdk9 and SGV1

DIOPT Version :9

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_015487.1
• Gene: SGV1 / 856290
• SGDID: S000006365
• Length: 657
• Species: Saccharomyces cerevisiae
• Alignment Length: 355
• Identity: 143/355 - (40%)
• Similarity: 209/355 - (58%)
• Gaps: 40/355 - (11%)

  Fly    48 NKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVN 112
            |.|.:..|:||||||||:|....:..:: |||||:::..||:.|||||.|||.||:.|.|:|::.
Yeast    58 NHYREDEKLGQGTFGEVYKGIHLETQRQ-VAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIK 121

  Fly   113 LIEICR------TKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYY 171
            |||:..      |.|.::|.::| ||::..:...||:|:|.|..:...:.:||.:|.|:|.||.|
Yeast   122 LIEMVYDHSPDITNAASSNLHKS-FYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNY 185

  Fly   172 IHSNKILHRDMKAANVLITKHGILKLADFGLARA-FSIPKN-------ESKNRYTNRVVTLWYRP 228
            ||..|.:|||:|.||:||..:|:||||||||||. :..|.|       .|..:||:.|||.|||.
Yeast   186 IHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRA 250

  Fly   229 PELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVW------PG 287
            |||:|||:.|...||:||.||:.||.:.:.||:||.|:..|...|.:|.|:.|.:.|      ||
Yeast   251 PELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPG 315

  Fly   288 VEELELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPM 352
            .|        ....|.|..::||...|: .:||.|.|.:||.|||.||:.|.:|.:|.:|..||:
Yeast   316 AE--------LTTTNYKPTLRERFGKYL-SETGLDFLGQLLALDPYKRLTAMSAKHHPWFKEDPL 371

  Fly   353 PSDLSKM---------LSQHLQSMFEYLAQ 373
            ||:...:         :.::.:.|.:.|:|
Yeast   372 PSEKITLPTEESHEADIKRYKEEMHQSLSQ 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	135/318 (42%)
SGV1	NP_015487.1	STKc_BUR1	50..366	CDD:270849	135/318 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346374
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000444
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104394
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R186
SonicParanoid	1	1.000	-	-		X3758
TreeFam	1	0.960	-	-
	8	7.730