Protein Alignment Cdk9 and CDK11A

DIOPT Version :9

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001300825.1
• Gene: CDK11A / 728642
• HGNCID: 1730
• Length: 783
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 148/440 - (33%)
• Similarity: 220/440 - (50%)
• Gaps: 76/440 - (17%)

  Fly     5 SHMLQQP----------SGSTPSNVGSSSSRTMSLMEKQKYIED----------YDFPY------ 43
            :|:|..|          |......||..:.::.:|.|.. |:.|          .:.|.
Human   355 NHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD-YVPDSPALLPIELKQELPKYLPALQ 418

  Fly    44 -CDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKH 107
             |....:::.:.:|.:||:|.|::|::|| ..:.||:|::.|:.||||||||:||||..:...:|
Human   419 GCRSVEEFQCLNRIEEGTYGVVYRAKDKK-TDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 482

  Fly   108 ENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYI 172
            .|:|.:.||      .........|:|.::.||||..|:..|...|..||:|.:|.|||.|:.::
Human   483 PNIVTVREI------VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 541

  Fly   173 HSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRN 237
            |.|.|||||:|.:|:|::..||||:.||||||.:..|    ...||..|||.|||.||||||.:.
Human   542 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKE 602

  Fly   238 YGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKN 302
            |...||||..|||..|:.|:.|:..||:|..|:..:.:..|:.:..:|||..||.:.|.:...::
Human   603 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 667

  Fly   303 QKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKMLSQHLQSM 367
            ....:::|....:.|| |.||::|.||..|.:||.|:..|.|::|...|:|.|         .||
Human   668 PYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID---------PSM 722

  Fly   368 FEYLAQPRRSNQMR--------------NYHQ-----------QLTTMNQ 392
            |.  ..|.:|.|.|              .|.|           .|||.||
Human   723 FP--TWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQ 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	121/326 (37%)
CDK11A	NP_001300825.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..396		9/41 (22%)
		STKc_CDC2L1	420..711	CDD:173741	119/302 (39%)
		PLN00009	423..713	CDD:177649	119/301 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	721..783		14/52 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920