Protein Alignment Cdk9 and Cdkl1

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001020292.1
• Gene: Cdkl1 / 314198
• RGDID: 1305080
• Length: 352
• Species: Rattus norvegicus
• Alignment Length: 350
• Identity: 116/350 - (33%)
• Similarity: 178/350 - (50%)
• Gaps: 32/350 - (9%)

  Fly    49 KYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPI---TALREIRILQLLKHENV 110
            ||||:.|||:|::|.|||.| .:...:.||:|:.|   |.|..|:   .||||||:|:.|||.|:
  Rat     3 KYEKIGKIGEGSYGVVFKCR-NRDTGQIVAIKRFL---ETEDDPVIKKIALREIRMLKQLKHPNL 63

  Fly   111 VNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSN 175
            |:|:|:.|.|        ...:|||::|.|.:...|...........:|.:..|.|..:.:.|.:
  Rat    64 VSLLEVFRRK--------RRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKH 120

  Fly   176 KILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGP 240
            ..:|||:|..|:|||||.::||.|||.||..:.|    .:.||:.|.|.|||.||||:||..|||
  Rat   121 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGP----GDYYTDYVATRWYRSPELLVGDTQYGP 181

  Fly   241 PVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKNQKR 305
            |||:|..||:.||:.:..|:..|.::..||..|.:..|...|.........:.:..:::|..:..
  Rat   182 PVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDM 246

  Fly   306 RVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKMLSQHLQSMFEY 370
            ...|...|.: ..:....|...|.:||.:|:..:..|.|.:|  |.: .|:.::...|
  Rat   247 ETLELKFPNI-SYSALGFLKGCLHMDPAERLTCEQLLQHPYF--DSI-RDVGELARPH------- 300

  Fly   371 LAQPRRSNQMRNYHQQLTTMNQKPQ 395
             .:|.|.. :|...:.||.:...||
  Rat   301 -DKPTRKT-LRQSRKHLTGLQHLPQ 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	105/300 (35%)
Cdkl1	NP_001020292.1	STKc_CDKL1_4	2..287	CDD:270837	105/300 (35%)
		[NKR]KIAxRE	45..51		2/5 (40%)