Protein Alignment Cdk9 and cdk-9

DIOPT Version :9

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_492906.2
• Gene: cdk-9 / 173023
• WormBaseID: WBGene00000410
• Length: 478
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 197/422 - (46%)
• Similarity: 265/422 - (62%)
• Gaps: 35/422 - (8%)

  Fly    13 GSTPSNVGSSSSRTMSLMEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFV 77
            |.||:...........|...||..:...:|:..:.:.|||:.|||||||||||||| .|...:.|
 Worm    48 GQTPNGTNYELEVKQQLSNYQKLFDQATYPFIRDVSTYEKLNKIGQGTFGEVFKAR-CKNTGRMV 111

  Fly    78 AMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLIEICRTKATATNGY--RSTFYLVFDFCEH 140
            |:||:||:|||||||||||||:::|:.|||.|:.:|||:|..|:|.|.|.  |:|||||...|.|
 Worm   112 ALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAH 176

  Fly   141 DLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARA 205
            ||||||||..::.||..||.:|:.|::||..:|.:||||||||||||||:|.||||||||||||.
 Worm   177 DLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARP 241

  Fly   206 FSIPKNESKNR--YTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQ 268
            |...:|.:..|  ||||||||||||||||||||.||..:|:|||||||||||||.|||||:|||:
 Worm   242 FVQRENGAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQK 306

  Fly   269 QLTFISQLCGSFTPDVWPGVEELELYKSIE------LPKNQKRRVKERLRPYVK----------- 316
            ||..||.||||...||||....:.|:.::.      ||:.:.|.:..:::..:|
 Worm   307 QLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPF 371

  Fly   317 -----------DQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMP-SDLSKMLSQHLQSMFE 369
                       |.....||:.||.:||.||..:|.|.:..:|:.||:| :::..::.....|.||
 Worm   372 GKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWFFKDPVPMANVQDLMDTIPNSQFE 436

  Fly   370 Y-LAQPRRSNQMRNYHQQLTTMNQKPQDNSMI 400
            | :.:...:|:.|:.:.|.....|:.:.::.|
 Worm   437 YTVGKGAHANRGRHQNAQQRPNQQQARPSNAI 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	178/341 (52%)
cdk-9	NP_492906.2	STKc_CDK9	72..413	CDD:270848	178/341 (52%)
		S_TKc	85..413	CDD:214567	177/328 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167022
Domainoid	1	1.000	331	1.000	Domainoid score	I613
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55566
Inparanoid	1	1.050	356	1.000	Inparanoid score	I1307
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48642
OrthoDB	1	1.010	-	-		D344403at33208
OrthoFinder	1	1.000	-	-		FOG0000444
OrthoInspector	1	1.000	-	-		oto18004
orthoMCL	1	0.900	-	-		OOG6_104394
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R186
SonicParanoid	1	1.000	-	-		X3758
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940