DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17807 and TRM9

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_013698.1	Gene:	TRM9 / 854994	SGDID:	S000004476	Length:	279	Species:	Saccharomyces cerevisiae

Alignment Length:	263	Identity:	95/263 - (36%)
Similarity:	139/263 - (52%)	Gaps:	52/263 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 QAITLEQQNVHEVYDKIADHFSETRHTPWPQVSEFLDSFEPQSVVLDIGCGNGKYLSCNPLLLSV 419
            ||...||:.||:||::||.|||:||:.|||.|::||.:....|:.:|:||||||||..||.:..:
Yeast     5 QAAEKEQEYVHKVYNEIAPHFSQTRYKPWPIVTQFLKTRPMGSIGIDVGCGNGKYLGVNPDIYII 69

  Fly   420 GCDRAQGLL--AVGRRKGQNVFRCDCLVVPVRSSSIDGCISIAVIHHLATKERRLAALQEMARVL 482
            |.||:.||:  |.|.....|:...|.|.:|.::.:.|..|||||:||.:|:|||:..::.:...|
Yeast    70 GSDRSDGLIECARGINPSYNLLVADGLNLPHKNETFDFAISIAVVHHWSTRERRVEVIRHVLSKL 134

  Fly   483 RPGGRALVYVWA-------------------------KDQRKNDKKSTYLRQNKA------VN-- 514
            |.||:||:|.||                         |.:.|...|||...:.|.      :|
Yeast   135 RQGGQALIYCWALEQGSSRRGYHEGMEQDVFVPWVLPKSKSKPKTKSTPPAKVKTRPKPNLMNIP 199

  Fly   515 -KERTTEQQQRQKQHQELEQQLSNNNPLPVHTNRTEFQQQDVLVPWKTKDEQKTTYLRYYHVFEE 578
             ||| :|..||.|:.|:..:.|.:|:         |.||||      .:.|::....||||::.|
Yeast   200 PKER-SEYLQRWKEEQQRSKSLDDND---------EKQQQD------QEQEREEVKYRYYHLYRE 248

  Fly   579 QEL 581
            .||
Yeast   249 GEL 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877
		2OG-FeII_Oxy	136..322	CDD:304390
		Methyltransf_11	400..490	CDD:285453	39/91 (43%)
TRM9	NP_013698.1	Methyltransf_25	51..138	CDD:404528	36/86 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345844
Domainoid	1	1.000	80	1.000	Domainoid score	I2016
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H44488
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1867
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001370
OrthoInspector	1	1.000	-	-		oto99628
orthoMCL	1	0.900	-	-		OOG6_100549
Panther	1	1.100	-	-	LDO	PTHR13069
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1711
SonicParanoid	1	1.000	-	-		X865
TreeFam	0	0.000	Not matched by this tool.
	12	11.720