DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and Alkbh7

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_079814.1	Gene:	Alkbh7 / 66400	MGIID:	1913650	Length:	221	Species:	Mus musculus

Alignment Length:	189	Identity:	53/189 - (28%)
Similarity:	83/189 - (43%)	Gaps:	23/189 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 FVTEEEESTLLRAIGEDGRTSEVTGSLKHRNVKHFGFEFLYGTNNVDPSKPLEQSIPS-ACDILW 206
            |:::|||.||         |.|:...|:.|.     :|:.:....:...:..|:|..| |..::.
Mouse    39 FLSQEEEDTL---------TRELEPQLRRRR-----YEYDHWDAAIHGFRETEKSCWSDASQVIL 89

  Fly   207 PRLNSFASTWDWSSPDQLTVNEYEPGHGIPPHVDTHSAFLDPILSLSLQSDVVMDF---RRGDDQ 268
            .|:.:.|...|.|....:.|.:.||...|.||||:.......|..|||.|..||..   :..:..
Mouse    90 QRVRAAAFGPDQSLLSPVHVLDLEPRGYIKPHVDSVKFCGSTIAGLSLLSPSVMKLVHTQEPEQW 154

  Fly   269 VQVRLPRRSLLIMSGEARYDWTHGIRPKHIDVVPSASGGLTTQARGKRTSLTFRRLRKG 327
            :::.|...||.|:.|.||||::|.|....     .:..|.....||:|.|:..|.|.:|
Mouse   155 LELLLEPGSLYILRGSARYDFSHEILRDE-----ESFFGEHRVPRGRRISVICRSLPEG 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877
		2OG-FeII_Oxy	136..322	CDD:304390	50/182 (27%)
		Methyltransf_11	400..490	CDD:285453
Alkbh7	NP_079814.1	2OG-FeII_Oxy	33..200	CDD:304390	49/179 (27%)
Alkbh7	NP_079814.1	Alpha-ketoglutarate binding. /evidence=ECO:0000250\|UniProtKB:Q9BT30	197..199		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3145
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810