DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and PRMT7

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_011521414.1	Gene:	PRMT7 / 54496	HGNCID:	25557	Length:	714	Species:	Homo sapiens

Alignment Length:	362	Identity:	75/362 - (20%)
Similarity:	114/362 - (31%)	Gaps:	136/362 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 CLAIIKSDCEV-SPSAEPTPYLAVLNVGLSNGLTEECLLTEAAATGGKVIQVVMLP-GKSYC--F 83
            |.||     || .|.|:     |.:.:...||.:::..:....:|     :|.:.| |...|  .
Human    90 CYAI-----EVFKPMAD-----AAVKIVEKNGFSDKIKVINKHST-----EVTVGPEGDMPCRAN 139

  Fly    84 FICASLEDSQLI-------YEGMH------NISTIGQQGAVAYLSYIRQLPALAGKSEWNKPLPR 135
            .:...|.|::||       ||..|      |...:..:..|     ..||........|||..|
Human   140 ILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATV-----YAQLVESGRMWSWNKLFP- 198

  Fly   136 GLHIIADFVTEEEESTLLRAIGEDGRTSEVTGSLKHRNVKHFGFEFLYGTNNVDPSKPLEQ--SI 198
             :|:                     :||                   .|...:.|...:|.  ..
Human   199 -IHV---------------------QTS-------------------LGEQVIVPPVDVESCPGA 222

  Fly   199 PSACDILWPRLNSFASTWDWSSPDQLTV-NEYEP------GHGIPPHVDTHSAFLDPILSLSLQS 256
            ||.|||   :||..       ||...|| ::..|      ...:......||...:|:.|...|.
Human   223 PSVCDI---QLNQV-------SPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQV 277

  Fly   257 -----DVVMD------------FRRGD-DQVQVR---------LPRRSLLIMSGEARYDWTHGIR 294
                 |:.||            :...| :::|.|         ||:.. .::.|.|.|...|
Human   278 VLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEE-PVVQGSALYLVAH--- 338

  Fly   295 PKHIDVVPSASGGLTTQARGKRTSLTFRRLRKGPCDC 331
              |.|.....|...|:..:.:|.    |::|. .|||
Human   339 --HDDYCVWYSLQRTSPEKNERV----RQMRP-VCDC 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877	17/94 (18%)
		2OG-FeII_Oxy	136..322	CDD:304390	40/221 (18%)
		Methyltransf_11	400..490	CDD:285453
PRMT7	XP_011521414.1	AdoMet_MTases	37..>186	CDD:302624	26/115 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900