DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and PRMT1

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001527.3	Gene:	PRMT1 / 3276	HGNCID:	5187	Length:	371	Species:	Homo sapiens

Alignment Length:	245	Identity:	47/245 - (19%)
Similarity:	74/245 - (30%)	Gaps:	116/245 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VLNVGLSNGLTEECLLTEAAATGG----------------KVIQ-------VVMLPGK------- 79
            ||:||...|:.  |:.  ||..|.                |:::       |.::.||
Human    92 VLDVGSGTGIL--CMF--AAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELP 152

  Fly    80 ------------SYCFFICASLEDSQLIYEGMHNISTIGQQGAVAYLSYIRQLPALAGKSEWNKP 132
                        .||.|           ||.|.|                   ..|..:.:|..|
Human   153 VEKVDIIISEWMGYCLF-----------YESMLN-------------------TVLYARDKWLAP 187

  Fly   133 LPRGLHIIADFVTEEEESTLLRAIGEDGRTSEVTGSLKHRNVKHFGFEFLYG-----TNNVDPSK 192
                     |.:...:.:||.....||         .::::.|...:|.:||     ..:|...:
Human   188 ---------DGLIFPDRATLYVTAIED---------RQYKDYKIHWWENVYGFDMSCIKDVAIKE 234

  Fly   193 PL------EQSIPSAC-----DILWPRLNSFASTWDWSSPDQLTV--NEY 229
            ||      :|.:.:||     ||...::.....|    ||..|.|  |:|
Human   235 PLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFT----SPFCLQVKRNDY 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877	20/115 (17%)
		2OG-FeII_Oxy	136..322	CDD:304390	24/112 (21%)
		Methyltransf_11	400..490	CDD:285453
PRMT1	NP_001527.3	AdoMet_MTases	92..192	CDD:100107	24/142 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900