DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and Alkbh2

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_006249560.1	Gene:	Alkbh2 / 304578	RGDID:	1306377	Length:	287	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	62/297 - (20%)
Similarity:	98/297 - (32%)	Gaps:	109/297 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 QQGAVAYLSY----IRQLPALAGKSEWNKPLPRGLHIIAD------FVTEEEESTLLRAIGEDGR 161
            :.|.|..|:|    ..:.|..:|...|          :|.      |:...:...:..|..|...
  Rat    16 EHGCVPVLAYPAGRRTEAPCFSGTRLW----------LAGGGGMDRFLVRPDRGDIQGAAEEPAP 70

  Fly   162 TSEVTGSLKHRNVKHFGFEFLYGTNNVDPS------------KPLEQSIPSACDIL--------W 206
            |.|.:|.::....:||..|.|    |.|.:            :.|||.:......|        |
  Rat    71 TGEASGDMQSPGWQHFRAEGL----NCDYTVLFRKAEADQIFRELEQEVEYFTGALAKVQVFGKW 131

  Fly   207 ---PR----LNSFASTWDWS----SP-----------DQ-----------LTVNEYEPG--HGIP 236
               ||    ......|:.:|    :|           ||           :.||.|:.|  | |.
  Rat   132 HSVPRKQATYGDAGLTYTFSGLTLTPKPWIPVLERVRDQVCRVTGQTFNFVLVNRYKDGCDH-IG 195

  Fly   237 PHVDTHSAFL--DPILSLSLQS--DVVMDFRRGDDQ----------VQVRLPRRSLLIMSGEARY 287
            .|.|......  .||.|:|..:  |::  ||..|.:          |:::|...|||:|:.....
  Rat   196 EHRDDERELAPGSPIASVSFGACRDIL--FRHKDSRGKRPRRAVEVVRLQLAHGSLLMMNHPTNT 258

  Fly   288 DWTHGIRPKHIDVVPSASGGLTTQARGKRTSLTFRRL 324
            .|.|.:..:...:.|             |.:||||::
  Rat   259 HWYHSLPIRKRVLAP-------------RINLTFRKI 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877	4/15 (27%)
		2OG-FeII_Oxy	136..322	CDD:304390	53/260 (20%)
		Methyltransf_11	400..490	CDD:285453
Alkbh2	XP_006249560.1	2OG-FeII_Oxy_2	98..280	CDD:290266	40/197 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3145
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900