DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17807 and ALKBH3

DIOPT Version :9

Sequence 1:NP_611690.2 Gene:CG17807 / 37585 FlyBaseID:FBgn0034748 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_631917.1 Gene:ALKBH3 / 221120 HGNCID:30141 Length:286 Species:Homo sapiens


Alignment Length:123 Identity:34/123 - (27%)
Similarity:47/123 - (38%) Gaps:41/123 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   217 DWSSPDQLTVNEYEPGHGIPPHVDTHSAFLDPILSLSLQSDVVMDFRR-------GD----DQVQ 270
            ||.|.|       ||..|..|          .|.|||..:....:.|:       ||    ::|:
Human   189 DWHSDD-------EPSLGRCP----------IIASLSFGATRTFEMRKKPPPEENGDYTYVERVK 236

  Fly   271 VRLPRRSLLIMSGEARYDWTHGIRPKHIDVVPSASGGLTTQARGKRTSLTFRRLRKGP 328
            :.|...:||||.|..:.||.|.: ||..            .:|..|.:||||.:...|
Human   237 IPLDHGTLLIMEGATQADWQHRV-PKEY------------HSREPRVNLTFRTVYPDP 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17807NP_611690.2 RRM_ALKBH8 40..119 CDD:240877
2OG-FeII_Oxy 136..322 CDD:304390 31/115 (27%)
Methyltransf_11 400..490 CDD:285453
ALKBH3NP_631917.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 21..45
2OG-FeII_Oxy 90..275 CDD:328754 31/115 (27%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:Q6NS38 141..143
Alpha-ketoglutarate binding. /evidence=ECO:0000269|PubMed:16858410, ECO:0007744|PDB:2IUW 179..181
Alpha-ketoglutarate binding. /evidence=ECO:0000269|PubMed:16858410, ECO:0007744|PDB:2IUW 269..275 3/5 (60%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3145
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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