DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and C35D10.12

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_498018.1	Gene:	C35D10.12 / 183240	WormBaseID:	WBGene00016448	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	364	Identity:	92/364 - (25%)
Similarity:	151/364 - (41%)	Gaps:	119/364 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   359 LEQQNVHEVYDKIADHFSETRHTP-----WPQVSEFLDSFEPQSVVLDIGCGNGKYLSCNPLLLS 418
            :||:.||.:|.::|. :.:..|.|     ||:|.:|:|.....|::||:|||..||.|....:
Worm     8 VEQEYVHSIYSRLAT-YQQKEHKPSSPRIWPRVRQFVDQQSAGSIILDVGCGEAKYTSQKSHV-- 69

  Fly   419 VGCDRAQGLLAVGRRKGQNVFRCDCLVVPVRSSSIDGCISIAVIHHLATKERRLAALQEMARVLR 483
            :|.|....:|:..::...::...|.:.:|:|..|:|..::::|||||||..||...|||.:|.||
Worm    70 IGFDTCSEVLSSSKKDDIDLCLADAINIPIRDDSVDAILNVSVIHHLATTARRRQVLQECSRCLR 134

  Fly   484 PGGRALVYVWAKDQRKNDKKSTYLRQNKAV--NKERT--------------TEQQQR-------- 524
            .||:.|:|.||.:| .|.|   :..|:..|  |...|              |.::||
Worm   135 IGGQMLIYAWAFEQ-PNGK---FASQDILVPWNMHETAIGGRLPKVKFHLNTTKEQRVIAASIPV 195

  Fly   525 --------QKQHQ-ELEQQLSNNNPLPVHT----NRTEFQQQ----------------------- 553
                    ||... .|.:.:|..:.||..:    |...:..|
Worm   196 NISDGSIPQKWFSGVLSKVVSLTDQLPYFSKRCPNSPAYSNQSTPTGSLSSPMVQKLPSAAPQFL 260

  Fly   554 ----------------------DVLVPWKTKDEQ----------------------KTTYLRYYH 574
                                  .:|||   .:||                      :.|:.|:||
Worm   261 PTTNSLISGIKRWSPMLGRRLASLLVP---VEEQFGEELAQTIMRESITEAMATLREVTFYRFYH 322

  Fly   575 VFEEQELENLVSQVHEVQLIKSYYDQGNHCAIFEKLSNN 613
            ||::.||.:||..|..::::.:.::.||.|.|.||::.|
Worm   323 VFKDGELADLVDSVESLKVVSATFEHGNWCVIAEKVAAN 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877
		2OG-FeII_Oxy	136..322	CDD:304390
		Methyltransf_11	400..490	CDD:285453	33/89 (37%)
C35D10.12	NP_498018.1	Methyltransf_11	53..141	CDD:369777	33/89 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D434082at33208
OrthoFinder	1	1.000	-	-		FOG0001370
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100549
Panther	1	1.100	-	-	O	PTHR13069
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1711
SonicParanoid	1	1.000	-	-		X865
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.850