Protein Alignment CG17807 and alkb-8

DIOPT Version :10

• Sequence 1: NP_611690.2
• Gene: CG17807 / 37585
• FlyBaseID: FBgn0034748
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_497751.1
• Gene: alkb-8 / 175476
• WormBaseID: WBGene00007581
• Length: 591
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 233/630 - (36%)
• Similarity: 332/630 - (52%)
• Gaps: 66/630 - (10%)

  Fly     4 EETQQKVNK----AKKADKKQRRCLAIIKSDCEVSPSAEPTPYLAVLNVGLSNGLT-EECLLTEA 63
            ||..:::.:    .|.|.|..:....:.:.|.:|..|.|||.||.|.|..:..|:: ||  |.|.
 Worm     5 EEKAKRIGERFEGGKLAKKVHKSIEQLKRHDPDVQISTEPTKYLLVSNSSILCGVSLEE--LEEI 67

  Fly    64 AATGGKVIQVVMLPGK-SYCFFICASLEDSQLIYEGMHNI--STIGQQGAVAYLSYIRQLPALAG 125
            .....::.:.::.|.| ||.|..|:|:|.|..:...:|.:  .::........:||:..||....
 Worm    68 FLPLDELAEFIVYPNKRSYSFVQCSSIEKSIQVRTELHGLIPPSLKNSHQPFAISYVENLPEATK 132

  Fly   126 KSEWNKPLPRGLHIIADFVTEEEESTLLRAIGEDGRTSEVTGSLKHRNVKHFGFEFLYGTNNVDP 190
            ..::.   |..|.||.::|:.:.|..|:..:.......    |||||.|.|||..|.|.||:...
 Worm   133 CEDFR---PANLKIIEEYVSSDLEKELVDLVTNHPSVQ----SLKHRAVVHFGHVFDYSTNSASE 190

  Fly   191 SKPLEQSIPSACDILWPRLNSFASTWDWSSPDQLTVNEYEPGHGIPPHVDTHSAFLDPILSLSLQ 255
            .|..: .||...:.|..||  .:..:....|||:|.|.||.|||||.|.||||||.|||:|:||.
 Worm   191 WKEAD-PIPPVINSLIDRL--ISDKYITERPDQVTANVYESGHGIPSHYDTHSAFDDPIVSISLL 252

  Fly   256 SDVVMDFRRGDDQVQ---VRLPRRSLLIMSGEARYDWTHGIRPKHIDVVPSASGGLTTQARGKRT 317
            |||||:|:.|.:..:   |.|..|||.::.||:||.|.|||..:..||.|..:..:..|.   |.
 Worm   253 SDVVMEFKDGANSARIAPVLLKARSLCLIQGESRYRWKHGIVNRKYDVDPRTNRVVPRQT---RV 314

  Fly   318 SLTFRRLRKGPCDCSYPALCDTQ---QTKVP--QELHASLAAQAITLEQQNVHEVYDKIADHFSE 377
            |||.|::|:.||:|.:...||..   :..||  ::|       |:.||...|.:||:.||.||.|
 Worm   315 SLTLRKIRRKPCECEWKEFCDWDRKGEMSVPSNEDL-------ALKLENSYVSDVYENIASHFDE 372

  Fly   378 TRHTPWPQVSEFLDSFEPQSVVLDIGCGNGKYLSCNPLLLSVGCDRAQGLLAVGRRKGQNVFRCD 442
            |||:.|..|.:|::.....||:.|:||||||||.....||.:|||...||..:.|:|..:|.|||
 Worm   373 TRHSSWKAVKQFINEIPRGSVMYDVGCGNGKYLIPKDGLLKIGCDMCMGLCDIARKKDCHVARCD 437

  Fly   443 CLVVPVRSSSIDGCISIAVIHHLATKERRLAALQEMARVLRPGGRALVYVWAKDQRKNDKKSTYL 507
            .|.:|.|..|.|..|||||:||:||.|||...::|:.||::||.:..|.||:.||.:::...  :
 Worm   438 ALALPFRYESADAAISIAVLHHIATFERRKRLIEELLRVVKPGSKICVTVWSMDQSQSEYAK--M 500

  Fly   508 RQNK-------AVNKERTTEQQQRQKQHQELEQQLSNNNPLPVHTNRTEFQQQDVLVPWKTKDEQ 565
            |.||       ||:.|.|                 ...|.|.||..: :|:|||||||| |.|::
 Worm   501 RGNKDDVAAAPAVSSEET-----------------QTTNRLKVHDGK-DFEQQDVLVPW-TIDQK 546

  Fly   566 KTTYLRYYHVFEEQELENLVSQVHEVQLIKSYYDQGNHCAIFEKL 610
            ..|:|||||||.|.|.|.|:..|...:||....:|||:..|.:|:
 Worm   547 GETFLRYYHVFREGEAEKLIESVQGCKLISVEKEQGNYIIIAKKI 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:409865	22/82 (27%)
		2OG-FeII_Oxy	136..322	CDD:473886	78/188 (41%)
		UbiE	368..498	CDD:441828	62/129 (48%)
alkb-8	NP_497751.1	RRM_SF	45..125	CDD:473069	22/81 (27%)
		2OG-FeII_Oxy	159..319	CDD:473886	72/169 (43%)
		UbiE	363..489	CDD:441828	60/125 (48%)