DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and METTL27

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_016867266.1	Gene:	METTL27 / 155368	HGNCID:	19068	Length:	271	Species:	Homo sapiens

Alignment Length:	157	Identity:	35/157 - (22%)
Similarity:	59/157 - (37%)	Gaps:	38/157 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   353 AAQAITLEQQNVHEVYDKIADHFSE-----------------TRHTPWPQVSEFLDSFEPQSVVL 400
            ||..|....|.:| .||:.|..:.:                 |:..|.|..|         :::|
Human    18 AAHGIPDLAQKLH-FYDRWAPDYDQDVATLLYRAPRLAVDCLTQALPGPPHS---------ALIL 72

  Fly   401 DIGCGNG---KYLSCNPLLLSVGCDRAQGLLAVGRRKG--QNVFRCDCLVVPVRS--SSIDGCIS 458
            |:.||.|   ..|.....|...|.|.:.|:|...:..|  |.:..|.....|:.|  .:.|   :
Human    73 DVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTLGQEPLPSPEGTFD---A 134

  Fly   459 IAVIHHLATKERRLAALQEMARVLRPG 485
            :.::..|:..:....|:.|: .|.:||
Human   135 VLIVGALSDGQVPCNAIPEL-HVTKPG 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877
		2OG-FeII_Oxy	136..322	CDD:304390
		Methyltransf_11	400..490	CDD:285453	23/93 (25%)
METTL27	XP_016867266.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900