DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and CARM1

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_954592.1	Gene:	CARM1 / 10498	HGNCID:	23393	Length:	608	Species:	Homo sapiens

Alignment Length:	151	Identity:	33/151 - (21%)
Similarity:	55/151 - (36%)	Gaps:	49/151 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 EQQNVHEVYDKIADHFSE--TRHTPWPQVSEFLDSFEPQSVVLDIGCGNGKYLSCNPLLLSVGCD 422
            :|||:.:.|.:...:...  ..||      :|.|     .:|||:|||:|        :||....
Human   158 QQQNMMQDYVRTGTYQRAILQNHT------DFKD-----KIVLDVGCGSG--------ILSFFAA 203

  Fly   423 RAQGLLAVGRRK-----------------GQNVFRCDCLVVP--VRSSSIDGCISIAV---IHHL 465
            :|      |.||                 ..|......:|:|  |...|:...:.|.:   :.::
Human   204 QA------GARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYM 262

  Fly   466 ATKERRLAALQEMARVLRPGG 486
            ...||.|.:.....:.|:|.|
Human   263 LFNERMLESYLHAKKYLKPSG 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877
		2OG-FeII_Oxy	136..322	CDD:304390
		Methyltransf_11	400..490	CDD:285453	24/109 (22%)
CARM1	NP_954592.1	CARM1	34..138	CDD:288395
		PRMT5	<172..435	CDD:282971	29/137 (21%)
		Methyltransf_18	184..283	CDD:289607	25/117 (21%)
		Transactivation domain. /evidence=ECO:0000250	499..608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900