DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17807 and Prmt9

DIOPT Version :9

Sequence 1:	NP_611690.2	Gene:	CG17807 / 37585	FlyBaseID:	FBgn0034748	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001074709.1	Gene:	Prmt9 / 102182	MGIID:	2142651	Length:	846	Species:	Mus musculus

Alignment Length:	412	Identity:	83/412 - (20%)
Similarity:	140/412 - (33%)	Gaps:	148/412 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 LHIIADFVTEEEESTLLRAIGED------GRTSEVTGSLKHRNVKHFGFEFLYGTNNVDPSK-PL 194
            ||:       |.|..:::...:.      |..:|:..:|  .|::....|.|..|..::|:: .|
Mouse   472 LHL-------EHEMEVMKGFTKSKDLLSLGNEAELCSAL--ANLQTSRPEALEQTCMLEPTEIAL 527

  Fly   195 EQSIP---------------SACDILWP---------RLNSFASTWDW--SSPDQLTVNEYEPGH 233
            ..:||               .|.::||.         .:||.:...|.  |:.|...|.:...|.
Mouse   528 LNNIPYHEGFKTAMRKVLSSLAPELLWQPMDTHCQYMEMNSGSGQSDAAPSTADPFYVLDVSEGF 592

  Fly   234 GIPP-------HV--------DTHSAFLDPILSLSLQSDVVMDF--RRGDDQVQV-RLPRRSLLI 280
            .:.|       ||        |.|...||.|...:......::|  |..:|:..| :.|:...|
Mouse   593 SLLPILAGTLGHVKPYSSVEKDQHCIALDLIAEANHFPKETLEFWLRHIEDEAAVLQRPKSDKL- 656

  Fly   281 MSGEARYDWTHGIRPKHIDVV-PSASGGLTTQARGKRTSLTFRRLRKGPCDCSYPALCDTQQTKV 344
                    |:..|    :||: ||   ||..|...::.:::...|:.|              .|:
Mouse   657 --------WSIII----LDVIEPS---GLIQQELMEKAAISRCLLQSG--------------GKI 692

  Fly   345 -PQ-ELHASLAAQAITLEQQNVHEVYDKIADHFSETRHTPWPQVSEFLDSFE-PQSVVLDIGCGN 406
             || .|...:..::.||.:::.          ...|.||....::.|::.|: |..|.||:..
Mouse   693 FPQYVLMFGMLVESQTLVEESA----------VQGTEHTLGLNIAPFINQFQVPIRVCLDLSS-- 745

  Fly   407 GKYLSCNPLLLSVGCDRAQGLLAVGRRKGQNVFRCDCLVVPVRSSSIDGCISIAVIHHLATKERR 471
               |.|.||...|                 .:.|.| |:.|..::|              .||.:
Mouse   746 ---LPCVPLSQPV-----------------ELLRLD-LMTPYLNTS--------------NKEVK 775

  Fly   472 LAALQEMARVLRPGGRALVYVW 493
            :       ||.|.|....|..|
Mouse   776 V-------RVCRSGRVTAVPFW 790

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17807	NP_611690.2	RRM_ALKBH8	40..119	CDD:240877
		2OG-FeII_Oxy	136..322	CDD:304390	48/236 (20%)
		Methyltransf_11	400..490	CDD:285453	18/89 (20%)
Prmt9	NP_001074709.1	TPR 1	25..58
		TPR 2	67..100
		TPR_11	68..132	CDD:290150
		TPR repeat	68..95	CDD:276809
		TPR repeat	100..130	CDD:276809
		TPR 3	101..134
		AdoMet_MTases	148..>303	CDD:302624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900