DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33143 and FNDC4

DIOPT Version :9

Sequence 1:	NP_001368934.1	Gene:	CG33143 / 37583	FlyBaseID:	FBgn0053143	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_073734.1	Gene:	FNDC4 / 64838	HGNCID:	20239	Length:	234	Species:	Homo sapiens

Alignment Length:	205	Identity:	50/205 - (24%)
Similarity:	83/205 - (40%)	Gaps:	55/205 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VLFVNACLAGTI----PATPENITVTFLTPTAVRVSWQTQIDLKAHPIEKYIVTYKPTD------ 61
            ||.:.:|..|.:    |.:|.|:|||.|...:..|||..       |....::.|..:.
Human    31 VLLLVSCDLGFVRADRPPSPVNVTVTHLRANSATVSWDV-------PEGNIVIGYSISQQRQNGP 88

  Fly    62 -DRVVQDVAGSSEAIVLDRLLPSTQYSLVVTAIWQGKKYRSRGQIKFKTLD----LPKNTSQQDF 121
             .||:::|..::.|..|..|...:.|::.|.:|....:.....::.|:||.    ||.|:|.
Human    89 GQRVIREVNTTTRACALWGLAEDSDYTVQVRSIGLRGESPPGPRVHFRTLKGSDRLPSNSSS--- 150

  Fly   122 PPGIYGNSSNGARNVTNNASIFGDDVTSTATNTLTHGTTRELPTIRGVEIGIVLIVLMVWAGAIA 186
             ||                     |:|       ..|...|.|...| |:.|:::||::||..|.
Human   151 -PG---------------------DIT-------VEGLDGERPLQTG-EVVIIVVVLLMWAAVIG 185

  Fly   187 LFFNRWGKIR 196
            ||..::..|:
Human   186 LFCRQYDIIK 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33143	NP_001368934.1	FN3	19..93	CDD:238020	20/80 (25%)
		DUF4808	165..>230	CDD:374343	11/32 (34%)
		DUF4808	<534..597	CDD:374343
FNDC4	NP_073734.1	FN3	47..137	CDD:238020	22/96 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	122..160		12/69 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	197..234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910