DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33143 and FNDC5

DIOPT Version :9

Sequence 1:	NP_001368934.1	Gene:	CG33143 / 37583	FlyBaseID:	FBgn0053143	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_715637.2	Gene:	FNDC5 / 252995	HGNCID:	20240	Length:	212	Species:	Homo sapiens

Alignment Length:	197	Identity:	51/197 - (25%)
Similarity:	84/197 - (42%)	Gaps:	42/197 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PATPENITVTFLTPTAVRVSWQTQIDLKAHPIEKYIVTYKPTDDRV---VQDVAGSSEAIVLDRL 80
            |:.|.|:||..|...:..|||..   |:...:..:.::.:..|.|:   :|:|..::.:..|..|
Human    34 PSAPVNVTVRHLKANSAVVSWDV---LEDEVVIGFAISQQKKDVRMLRFIQEVNTTTRSCALWDL 95

  Fly    81 LPSTQYSLVVTAI-WQGKKYRSRGQIKFKTLDLPKNTSQQDFPPGIYGNSSNGARNVTNNASIFG 144
            ...|:|.:.|.|| .||:...|. .:.|||                       .|.....||...
Human    96 EEDTEYIVHVQAISIQGQSPASE-PVLFKT-----------------------PREAEKMASKNK 136

  Fly   145 DDVTSTATNTLTHGTTRELPTIRGVEIGIVLIVLMVWAGAIALFFNRWGKIRMLLPYQPDYKHEQ 209
            |:||....     |..::|   |..|:.|:::||.:|||.||||..::..|:   ..:|:...|:
Human   137 DEVTMKEM-----GRNQQL---RTGEVLIIVVVLFMWAGVIALFCRQYDIIK---DNEPNNNKEK 190

  Fly   210 LK 211
            .|
Human   191 TK 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33143	NP_001368934.1	FN3	19..93	CDD:238020	19/76 (25%)
		DUF4808	165..>230	CDD:374343	16/47 (34%)
		DUF4808	<534..597	CDD:374343
FNDC5	NP_715637.2	FN3	34..124	CDD:238020	25/93 (27%)
FNDC5	NP_715637.2	DUF4808	151..>203	CDD:318317	16/45 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910