DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps20 and chmp6b

DIOPT Version :9

Sequence 1:	NP_611686.2	Gene:	Vps20 / 37581	FlyBaseID:	FBgn0034744	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001003874.1	Gene:	chmp6b / 445397	ZFINID:	ZDB-GENE-040924-2	Length:	206	Species:	Danio rerio

Alignment Length:	206	Identity:	114/206 - (55%)
Similarity:	152/206 - (73%)	Gaps:	13/206 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGALFGKTSKKTAPSRITDQDKAVLQLKQQRDRLKQYQKRIETQLENDRLLARKCLQQGRKDRAK 65
            ||.||||  ||.  :|:|:||:||||||||||:||||||||..|::.:|.||::.|:.|:||:|.
Zfish     1 MGNLFGK--KKA--TRVTEQDRAVLQLKQQRDKLKQYQKRITLQMDKERQLAKQLLKDGKKDKAL 61

  Fly    66 LLLRKKKYQESLLTNADKQLENLEKLAADIEFAQVEMKVLDGLKAGNAALKKVHEMLDIDEVERI 130
            |||:||:||:.||...:.|:.|||::..||||||:||||::|||.||..|||:||:|.|:|||:|
Zfish    62 LLLKKKRYQDQLLEKTENQISNLERMVQDIEFAQIEMKVIEGLKVGNDCLKKMHEVLSIEEVEKI 126

  Fly   131 MDETREGIEKQQEIDAILTDVLTTQDEEDVLAELDAL---EAEEEQQKGAQLPDVPTEDLPIPAE 192
            ||||.:.||.|::||.:|...||.:|||.|||||:|:   ||:.|      ||:||.|:||...|
Zfish   127 MDETHDAIEYQKQIDEMLAGSLTQEDEEAVLAELEAITHGEADLE------LPEVPGEELPEVPE 185

  Fly   193 IESVEEPAKTK 203
            .|.|.|..:.|
Zfish   186 QEPVREKERVK 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps20	NP_611686.2	Snf7	22..186	CDD:281366	94/166 (57%)
chmp6b	NP_001003874.1	Snf7	18..179	CDD:304451	94/166 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..206		15/36 (42%)
		Type-2 MIT-interacting motif. /evidence=ECO:0000250	170..181		6/16 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586314
Domainoid	1	1.000	187	1.000	Domainoid score	I3268
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11607
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3625
OMA	1	1.010	-	-		QHG54090
OrthoDB	1	1.010	-	-		D1287094at2759
OrthoFinder	1	1.000	-	-		FOG0003546
OrthoInspector	1	1.000	-	-		otm25271
orthoMCL	1	0.900	-	-		OOG6_102807
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5973
SonicParanoid	1	1.000	-	-		X4514
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940