DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps20 and vps-20

DIOPT Version :9

Sequence 1:	NP_611686.2	Gene:	Vps20 / 37581	FlyBaseID:	FBgn0034744	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_490762.1	Gene:	vps-20 / 171654	WormBaseID:	WBGene00022027	Length:	208	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	94/212 - (44%)
Similarity:	139/212 - (65%)	Gaps:	4/212 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGALFGKTSKKTAPSRITDQDKAVLQLKQQRDRLKQYQKRIETQLENDRLLARKCLQQGRKDRAK 65
            ||.:|.|..|....:.::|||.|:|.||.|||::||..||.|..||.:|.||::.::.||||||.
Worm     1 MGGIFSKKEKSPKSAPVSDQDNAILALKTQRDKMKQMIKRKENCLEKERQLAKQLIKDGRKDRAL 65

  Fly    66 LLLRKKKYQESLLTNADKQLENLEKLAADIEFAQVEMKVLDGLKAGNAALKKVHEMLDIDEVERI 130
            |||:||:|||.::......|..:|::..|:|||:|:.:|.|||:.||.||||::::.||||::||
Worm    66 LLLKKKRYQEKIIDQTLNHLSKIEQMVNDLEFAEVQQRVTDGLRQGNEALKKMNQLFDIDEIDRI 130

  Fly   131 MDETREGIEKQQEIDAILTDVLTTQDEEDVLAELDALEAEEEQQKGAQLPDVPTEDLPIPAEIES 195
            |:||:|..|.|:||..:|:..|:..|..||..||:.|.|.|  ....|||:.|:.:|| .||.|.
Worm   131 MEETKEAAEYQEEISNMLSGQLSNTDVSDVEKELEDLLAAE--WGTVQLPEAPSHELP-EAERER 192

  Fly   196 VEEPAKTKATKKVLVEA 212
            .:|..|.: .:|:.:||
Worm   193 QKEKEKPR-REKIALEA 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps20	NP_611686.2	Snf7	22..186	CDD:281366	76/163 (47%)
vps-20	NP_490762.1	Snf7	23..184	CDD:281366	76/162 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162167
Domainoid	1	1.000	147	1.000	Domainoid score	I2775
eggNOG	1	0.900	-	-		E1_KOG2910
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11607
Inparanoid	1	1.050	173	1.000	Inparanoid score	I2725
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54090
OrthoDB	1	1.010	-	-		D1287094at2759
OrthoFinder	1	1.000	-	-		FOG0003546
OrthoInspector	1	1.000	-	-		oto18845
orthoMCL	1	0.900	-	-		OOG6_102807
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5973
SonicParanoid	1	1.000	-	-		X4514
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800