DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nsr and khdrbs2

DIOPT Version :9

Sequence 1:	NP_001286736.1	Gene:	nsr / 37577	FlyBaseID:	FBgn0034740	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001072215.1	Gene:	khdrbs2 / 779662	XenbaseID:	XB-GENE-490722	Length:	345	Species:	Xenopus tropicalis

Alignment Length:	336	Identity:	102/336 - (30%)
Similarity:	160/336 - (47%)	Gaps:	66/336 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 QKFLADLDEERKRLSAEFPLCALLIDESVDRVFST--GRIPGKEFYADVYHQRPMKITQKVFVPV 94
            :|:|.:|..|:..|...|.....|:||.:.:...:  .:..|::.|.|:...:.:|::::|.:||
Frog     4 EKYLPELMAEKDSLDPSFVHAMRLLDEEIVKFQDSEGNKEDGEKKYLDIISNKNIKLSERVLIPV 68

  Fly    95 NKFPKFNFARKILGPKGNSVRRLKEETNCKIVIKGRSSMRDRNKEEELRSSGDPRYAHLHKDLFL 159
            .::|||||..|:|||:|||::||:|||..|:.|.|:.||||:.||||||.|.:.::|||..:|.:
Frog    69 KQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKIKEEELRKSDEAKHAHLSDELHV 133

  Fly   160 EVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMN----PESAKKSNGLNMAPY 220
            .:...|||.|.|:|:::||.||:|:|:||.||::..||.|||..:|    .|..|.:.|
Frog   134 LLEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSDDSERGKGTRG------ 192

  Fly   221 RSI-FDKTIGGNRNGAPKYNNQIRRVTENPREVADMEEVEYDYDEHRMPPSRPSLGFEYSKPPPS 284
            |.| ...|...||.|.                               :.|:.|..|...::..|.
Frog   193 RGIRVPSTPSRNRGGV-------------------------------ISPAFPGRGASATRGAPI 226

  Fly   285 MTATNAT-----PFKRAYPYPTDMNRTREPPI---------------KSYKPNPYTILNKYINNR 329
            ...|.:|     |..||...||.......||:               :.|....|.|.....|::
Frog   227 TRGTISTVARGIPTPRAKAAPTTPGYRLPPPLTIETYDDYGYDDGFGEDYDEQSYDIYENNYNSQ 291

  Fly   330 APSDFVAQRYN 340
            ..|  |::.|:
Frog   292 TQS--VSEYYD 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nsr	NP_001286736.1	SF1_like-KH	87..206	CDD:239088	60/122 (49%)
khdrbs2	NP_001072215.1	Qua1	5..57	CDD:374463	12/51 (24%)
		SF1_like-KH	61..180	CDD:239088	59/118 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..224		13/82 (16%)
		Sam68-YY	263..317	CDD:374636	7/40 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..345
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10668
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9347
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020