DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nsr and khdrbs2

DIOPT Version :9

Sequence 1:	NP_001286736.1	Gene:	nsr / 37577	FlyBaseID:	FBgn0034740	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001070758.1	Gene:	khdrbs2 / 768147	ZFINID:	ZDB-GENE-061013-497	Length:	346	Species:	Danio rerio

Alignment Length:	352	Identity:	107/352 - (30%)
Similarity:	166/352 - (47%)	Gaps:	78/352 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KFLADLDEERKRLSAEFPLCALLIDESV-----DRVFSTGRIPGKEFYADVYHQRPMKITQKVFV 92
            |:|.:|..|::.|.|.|.....|:.|.:     |.:...|.:   :.|.|:...:.:|::::|.:
Zfish     5 KYLPELVAEKESLDASFVHAMRLLAEEIEKFEGDELRKDGEV---KKYLDIISNKNIKLSERVLI 66

  Fly    93 PVNKFPKFNFARKILGPKGNSVRRLKEETNCKIVIKGRSSMRDRNKEEELRSSGDPRYAHLHKDL 157
            ||.::|||||..|:|||:|||::||:|||..|:.|.|:.||||:.||||||.||:.:||||..||
Zfish    67 PVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDL 131

  Fly   158 FLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMN----PESAKKSNGLNM- 217
            .:.:...|||.|.|:|:::||.||:|:|:||.||::..||.|||..:|    |...:.:.|..:
Zfish   132 HVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSDDPSRGRSARGRGLR 196

  Fly   218 ------------------------APYRSIFDKT--------IGGNRN----GAPKYNNQIRRVT 246
                                    ||..::..:|        :...|.    |.|.|.....:.|
Zfish   197 LTSTASPRGRGSAAPPAPPGRGAAAPRGTVSSRTSVPTPARGVSAPRTRGTAGTPGYRAPSLQAT 261

  Fly   247 ENPRE---VADMEEVEYD------YDEHRMPPSRP-SLGFEYSKPPPSMTATNATPFKRAYPYPT 301
            ....|   ..|..:.|||      ||::....|:. |..:||..........|         |..
Zfish   262 HKTYEDYGYDDGYDGEYDDQSYESYDDNYSNQSKSVSEYYEYGHGNNDENYNN---------YEE 317

  Fly   302 DMNRTREPPIKS---------YKPNPY 319
            |...:| |.:|:         |:.:||
Zfish   318 DWISSR-PNLKAPASRLTRGGYRDHPY 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nsr	NP_001286736.1	SF1_like-KH	87..206	CDD:239088	63/122 (52%)
khdrbs2	NP_001070758.1	Qua1	6..57	CDD:292891	12/53 (23%)
		SF1_like-KH	61..180	CDD:239088	62/118 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..292		19/116 (16%)
		Sam68-YY	<281..>306	CDD:293176	6/24 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590101
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26159
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.810