DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nsr and qki2

DIOPT Version :9

Sequence 1:	NP_001286736.1	Gene:	nsr / 37577	FlyBaseID:	FBgn0034740	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_021335713.1	Gene:	qki2 / 393815	ZFINID:	ZDB-GENE-040426-1462	Length:	341	Species:	Danio rerio

Alignment Length:	334	Identity:	85/334 - (25%)
Similarity:	141/334 - (42%)	Gaps:	72/334 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EEQNQDQPTQDQPTYQPRLNEVAQKFLADLDEERKRLSAEFPLCAL------LIDESVDRVFSTG 67
            |.:.:.:||.|              :|..|..::|.:|:....|.:      |:||.:.||
Zfish     6 ETKEKPKPTPD--------------YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEIGRV---- 52

  Fly    68 RIPGKEFYADVYHQRPMKIT--------------QKVFVPVNKFPKFNFARKILGPKGNSVRRLK 118
               .|:.|.|..:....|.|              :|::|||.::|.|||..:||||:|.:.::|:
Zfish    53 ---RKDMYNDTLNGSTDKRTSELPDAVGPIAQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLE 114

  Fly   119 EETNCKIVIKGRSSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRK 183
            .||.|||:::|:.||||:.|||:.|  |.|.:.||::||.:.::..........::..|:.|::|
Zfish   115 AETGCKIMVRGKGSMRDKKKEEQNR--GKPNWEHLNEDLHVLITVEDSQNRAEIKLKRAVEEVKK 177

  Fly   184 YLIP--DDNDDVWHEQQRELMEMNPESAKKSNGLNMAPYRSIFDKTIGGNRNGAPKYNNQIRRVT 246
            .|:|  :..|.:...|..||..:|            ..||....|        :|.....:....
Zfish   178 LLVPAAEGEDSLKKMQLMELAILN------------GTYRDANIK--------SPALAFSLAATA 222

  Fly   247 ENPREVADMEEVEYDYDEHRMPPSRPSLGFEYSKPPPSMTATNA-TPFKRAYPYPTDMNRTREPP 310
            :.||.:.....|..:.......|:.|:|     .|......|:| .|....:|..|.:.:|.|..
Zfish   223 QAPRIMTGPTPVMPNAALRTPAPTAPTL-----MPLIRQIQTSALMPTGTPHPTATLLPQTPESG 282

  Fly   311 IKSYKPNPY 319
            | .|.|..|
Zfish   283 I-IYAPYDY 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nsr	NP_001286736.1	SF1_like-KH	87..206	CDD:239088	44/134 (33%)
qki2	XP_021335713.1	STAR_dimer	10..68	CDD:318695	16/78 (21%)
		SF1_like-KH	83..205	CDD:239088	44/135 (33%)
		PRK00708	139..299	CDD:331498	39/180 (22%)
		Quaking_NLS	314..341	CDD:293159
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590085
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.830