DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nsr and qkia

DIOPT Version :9

Sequence 1:	NP_001286736.1	Gene:	nsr / 37577	FlyBaseID:	FBgn0034740	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_571299.1	Gene:	qkia / 30471	ZFINID:	ZDB-GENE-990415-230	Length:	383	Species:	Danio rerio

Alignment Length:	346	Identity:	87/346 - (25%)
Similarity:	149/346 - (43%)	Gaps:	87/346 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EEQNQDQPTQDQPTYQPRLNEVAQKFLADLDEERKRLSAEFPLCAL------LIDESVDRVFSTG 67
            |.:.:.:|:.|              :|..|..|:|.:::...||.:      |:||.::||
Zfish     7 EVKERPRPSPD--------------YLMQLLNEKKLMTSLPNLCGIFTHLERLLDEEINRV---- 53

  Fly    68 RIPGKEFYAD----VYHQRPMK----------ITQKVFVPVNKFPKFNFARKILGPKGNSVRRLK 118
               .|:.|.|    :..:.|::          :.:|:||||.::|.:||..:||||:|.:.::|:
Zfish    54 ---RKDMYNDSVNGLVDKHPLELPEPVGPIVHLQEKLFVPVKEYPDYNFVGRILGPRGLTAKQLE 115

  Fly   119 EETNCKIVIKGRSSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRK 183
            .||.|||:::|||||||:.|||:.|  |.|.:.||::||.:.::..........::..|:.|::|
Zfish   116 AETGCKIMVRGRSSMRDKKKEEQNR--GKPNWEHLNEDLHVLITVEDTQTRAEIKMRRAVEEVKK 178

  Fly   184 YLIP--DDNDDVWHEQQRELMEMN-------------------PESAKKSNGLNMAPYRSIF-DK 226
            .|:|  :..|::...|..||..:|                   ..:|.:...|..||...:. ..
Zfish   179 LLVPAAEGEDNLKKMQLMELAILNGTYRDTNIKAPTLAFSLAAAAAAAQGPRLIAAPPGQVLPPA 243

  Fly   227 TIGGNRNGAPKYNNQIRRVTENPREVADMEEVEYDYDEHRMPPSRPSLGFEYSKPPPSMTATNAT 291
            |:...........|.||     |.::|.:           :|...|:|    ..|.|.......|
Zfish   244 TLRPPTPAGTPIMNIIR-----PTQMATV-----------LPNGTPTL----VPPTPDAGIIYTT 288

  Fly   292 PFKRAYPYPTDMNRTREPPIK 312
            |:.  |||........|.||:
Zfish   289 PYD--YPYALAPTSLLEYPIE 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nsr	NP_001286736.1	SF1_like-KH	87..206	CDD:239088	46/139 (33%)
qkia	NP_571299.1	STAR_dimer	11..69	CDD:293152	16/78 (21%)
		SF1_like-KH	84..206	CDD:239088	46/123 (37%)
		Quaking_NLS	356..383	CDD:293159
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590109
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740