DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nsr and Sf1

DIOPT Version :9

Sequence 1:	NP_001286736.1	Gene:	nsr / 37577	FlyBaseID:	FBgn0034740	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001104261.1	Gene:	Sf1 / 22668	MGIID:	1095403	Length:	639	Species:	Mus musculus

Alignment Length:	342	Identity:	79/342 - (23%)
Similarity:	145/342 - (42%)	Gaps:	74/342 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QDQPTQDQPTYQ---PRLNEVAQKFLADLDEERKRLSAEFPLCALLIDESVDRVFSTGRIPGKEF 74
            :|:....:|.|.   .|||....:....|:|||..|..|  :.||                ..:|
Mouse    77 EDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHTLITE--MVAL----------------NPDF 123

  Fly    75 YADVYHQRP-MKITQKVFVPVNKFPKFNFARKILGPKGNSVRRLKEETNCKIVIKGRSSMRD--- 135
            .....::.| .:::.||.:|.:::|:.||...::||:||:::.:::|.|.||:|:|:.|:::
Mouse   124 KPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV 188

  Fly   136 -RNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYL-----IPDDNDDVW 194
             |...:.|....:|.:|.:             .|.....:..|:.:||..|     .|:|.:|:.
Mouse   189 GRKDGQMLPGEDEPLHALV-------------TANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240

  Fly   195 HEQQRELMEMNPESAKKSNGLNMAPY-----RSIFDKTIGGNRNGAPKYNNQIR-RVTENPREVA 253
            ..|.|||..:|....:..|.: :.|:     |||.:.|:.....||....:..: :...:|:...
Mouse   241 KMQLRELARLNGTLREDDNRI-LRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQ 304

  Fly   254 DMEEVEYDY-------DEHRMP-----PSRPSLGFEYSKPPPSMTATNATPFKRAYPYPTDMNRT 306
            |...::.:|       .|..:|     .|.|:.....|.|.|:..|:|..|       |:.|:.|
Mouse   305 DKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPASNPPP-------PSLMSTT 362

  Fly   307 R-EPPIKSYKPN---PY 319
            : .||..:..|:   ||
Mouse   363 QSRPPWMNSGPSENRPY 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nsr	NP_001286736.1	SF1_like-KH	87..206	CDD:239088	33/127 (26%)
Sf1	NP_001104261.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44
		Nuclear localization signal. /evidence=ECO:0000255	15..19
		MSL5	17..257	CDD:227503	50/210 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..94		3/16 (19%)
		ZnF_C2HC	278..293	CDD:197667	2/14 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..584		17/62 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.731683	Normalized mean entropy	S1317
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.760