DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3927 and MSL5

DIOPT Version :9

Sequence 1:	NP_611681.1	Gene:	CG3927 / 37576	FlyBaseID:	FBgn0034739	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_013217.1	Gene:	MSL5 / 850807	SGDID:	S000004106	Length:	476	Species:	Saccharomyces cerevisiae

Alignment Length:	308	Identity:	75/308 - (24%)
Similarity:	117/308 - (37%)	Gaps:	91/308 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PSELTEKQNQDQPTYQ---PRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIP 65
            |.....:.....|.|.   .|.|...|::...|:.||.:|              |:....|  ||
Yeast    86 PPSRKNRSPSPPPVYDAQGKRTNTREQRYRKKLEDERIKL--------------VEIALKT--IP 134

  Fly    66 GKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRD 130
            ...| .|.| ::|.|...|.::||:::|..||.|.:|||:|.:||:|||:::|||.|:||.|:::
Yeast   135 YFVP-PDDY-KRPTKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKE 197

  Fly   131 RNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYL------------IPD 183
            .....:|     |..|...:|          |..|.. ||.:..:|:|.:            .|:
Yeast   198 GKNASDL-----PPGAMNFED----------PLHCLI-IADSEDKIQKGIKVCQNIVIKAVTSPE 246

  Fly   184 DNDDVWHEQQRELMEMNP--------------KSAKK-------------------------SNG 209
            ..:|:...|.|||.|:|.              |..|:                         |..
Yeast   247 GQNDLKRGQLRELAELNGTLREDNRPCPICGLKDHKRYDCPNRKIPNIQGIVCKICGQTGHFSRD 311

  Fly   210 LNMAPYR-SNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYD 256
            .|.:..| |.||:. ..:.|.||..:|.: ....|...:...:...||
Yeast   312 CNSSSQRMSRFDRN-ATVNNSAPIQSNDV-HYNSNTHPIQAPKRSRYD 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3927	NP_611681.1	SF1_like-KH	83..201	CDD:239088	40/129 (31%)
MSL5	NP_013217.1	MSL5	1..269	CDD:227503	60/216 (28%)
		AIR1	<267..386	CDD:227414	15/93 (16%)
		PHA03247	<363..435	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3083
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.731683	Normalized mean entropy	S1317
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.760