DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3927 and khdrbs2

DIOPT Version :9

Sequence 1:	NP_611681.1	Gene:	CG3927 / 37576	FlyBaseID:	FBgn0034739	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001070758.1	Gene:	khdrbs2 / 768147	ZFINID:	ZDB-GENE-061013-497	Length:	346	Species:	Danio rerio

Alignment Length:	191	Identity:	82/191 - (42%)
Similarity:	123/191 - (64%)	Gaps:	12/191 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KFLADLDAERKRLSAEFPLCALLIDESV-----DRVYSTGRIPGKEPFADVYQQKPMKIIQKVFV 87
            |:|.:|.||::.|.|.|.....|:.|.:     |.:...|.:   :.:.|:...|.:|:.::|.:
Zfish     5 KYLPELVAEKESLDASFVHAMRLLAEEIEKFEGDELRKDGEV---KKYLDIISNKNIKLSERVLI 66

  Fly    88 PVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDL 152
            ||.::|||||.||:|||:|||::||||||..|:.|.|:.||||:.||||||.||:.:||||..||
Zfish    67 PVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDL 131

  Fly   153 FLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMN----PKSAKKSNG 209
            .:.:...|||.|.|:|:::||.||:|:|:||.||::..||.|||..:|    |...:.:.|
Zfish   132 HVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSDDPSRGRSARG 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3927	NP_611681.1	SF1_like-KH	83..201	CDD:239088	65/121 (54%)
khdrbs2	NP_001070758.1	Qua1	6..57	CDD:292891	12/53 (23%)
		SF1_like-KH	61..180	CDD:239088	64/118 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..292		4/18 (22%)
		Sam68-YY	<281..>306	CDD:293176
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590102
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26159
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.810